Dynamic Behaviors in Coupled Neuron System with the Excitatory and Inhibitory Autapse under Electromagnetic Induction

Abstract

The induced current produced by electromagnetic induction can adjust the membrane potential of neuron through the feedback of a magnetic flux-controlled memristor. We adopt the numerical simulation method with the aim of investigating the synchronous behavior in the neuronal system that is coupled by chemical and electrical synapses under electromagnetic induction. Within the improved model, the effects of electromagnetic induction on neurons are described with additive memristive current on the membrane variable, and the memristive current is dependent on the variation of magnetic flow. The simulation results show that the two coupling modes play an important role in the synchronization of the system. By increasing the chemical synaptic feedback gain, we observe a transition from mixed oscillatory to periodic state at a critical value. In addition, two Hopf bifurcation points are found with the change of the external stimuli, and the state of neuron discharge is influenced by initial values. Furthermore, there is a domain of coupling strength and feedback gain values, in which the two coupled neuron system is synchronized and longer time lag is not conducive to the system synchronization.

Effects of temporally correlated noise on coherence resonance chimeras in FitzHugh-Nagumo neurons

“…The effects of electromagnetic radiation on the neural network have to be considered. It would be very interested to study the effects of chimeras on the neural network regulated by electromagnetic field [63][64][65] or electric field [66,67].…”

Evolving Evidence of Calreticulin as a Pharmacological Target in Neurological Disorders

“…Such intricate functions of CALR on [Ca 2+ ] ER could explain its vital roles in the CNS, for example, ER regulation of glial Ca 2+ waves helps in communicating signals to other neurons while Ca 2+ waves in the astrocytes network modulate long-range signaling and neural network activities, and cause release of ATP for wave propagation . On a larger scale, an indirect profound effect on calcium associated neurodynamics by CALR might alter electromagnetic induction between neurons during Ca 2+ wave propagation and impact calcium spiral waves governing mesoscopic cortical processing. , Since a better understanding of Ca 2+ dynamics can be obtained from neuronal biophysical models like transmitter release studies, assessing synaptic plasticity and other such studies could possibly lead to a better understanding of the regulatory role of CALR in Ca 2+ dynamics…”

“…56 On a larger scale, an indirect profound effect on calcium associated neurodynamics by CALR might alter electromagnetic induction between neurons during Ca 2+ wave propagation and impact calcium spiral waves governing mesoscopic cortical processing. 57,58 Since a better understanding of Ca 2+ dynamics can be obtained from neuronal biophysical models like transmitter release studies, assessing synaptic plasticity and other such studies could possibly lead to a better understanding of the regulatory role of CALR in Ca 2+ dynamics. 59 In summary, CALR could indirectly but effectively modulate regulation of neurite outgrowth, synaptogenesis, learning and memory, apoptosis, excitotoxicity, neurotransmitters release, and many other processes by regulating the ER calcium levels within neurons 51 (Figure 2).…”

Filtering properties of Hodgkin–Huxley neuron on different time-scale signals

“…The effects of systemic parameters and external factors on the electrical activity of neural models have been widely investigated in previous works, such as the external current [20], time delay [21], synapses [22,23], electric and magnetic fields [24,25], patch temperature [26], ionic channel blockage [27,28], various noises [29,30], etc.. Some neurological diseases are correlated with pathological enhancement synchronization in neurons, such as Parkinsonism [31].…”