Background: Cerebral palsy (CP) is one of the most common neurological disorders influences the abilities of the subjects to stand and walk. Various kinds of exercise are recommended to improve the stability of CP subjects during quiet standing. However, there is no evidence regarding the effects of core stability exercise on stability of CP subjects. Therefore, the aim of this research was to determine the efficiency of this exercise on stability of CP subjects.Method: Two group of normal and CP children were recruited in this study (10 subjects). The stability of the subjects was determined by use of a Kistler forceplate. The stability of the subjects was measured by Approximate entropy (ApEn) based on COP sways. The dynamic stability was evaluated by Berge balance scale. Ashworth scale was used to determine the spasticity of lower limb muscles groups. Results: The mean value of ApEn of CP patients in the anteroposterior and mediolateral directions were 0.465±0.11 and 0.426±0.99, respectively compared to 1.02±0.11 and 0.426±0.099 for normal subjects. There was a significant increase in ApEn of CP subjects before and after exercise (p-value<0.05). The mean value of Berge scale was 46.2±5.77 and 51.87±3.9 before and after exercise, respectively.Conclusion: As lower value of ApEn associated with decrease in complexity, higher rigidity and unstability, it can be concluded that CP subjects were unstable than normal subjects. Use of core stability exercise improves complexity of the system and improves the stability of the subjects due to its effect on muscular spasm.