Dynamic and distinct histone modifications facilitate human trophoblast lineage differentiation
Bum-Kyu Lee,
Joudi Salamah,
Elisha Cheeran
et al.
Abstract:The placenta serves as an essential organ for fetal growth throughout pregnancy. Histone modification is a crucial regulatory mechanism involved in numerous biological processes and development. Nevertheless, there remains a significant gap in our understanding regarding the epigenetic regulations that influence trophoblast lineage differentiation, a fundamental aspect of placental development. Here, through comprehensive mapping of H3K4me3, H3K27me3, H3K9me3, and H3K27ac loci during the differentiation of tro… Show more
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