Dye Release from Laser Irradiated Liposomes

Abstract

The main focus of this paper is to examine the consequence of laser pulses of narrow width impinging on phosphatidylcholine liposomes containing sulforhodamine dye molecules. The release of dye molecules following short-pulsed laser excitation and localized heating was measured and its dependence on laser excitation parameters studied. A characterization of the optimal conditions necessary for release of liposome contents can be applied to the targeted delivery of therapeutic drugs.