Dye detoxification by Lentinula edodes INCQS 40220

Bergsten-Torralba, L.R.; Zamith, Helena Pereira da Silva; Conde, Taline Ramos; Aiub, Cláudia Alessandra Fortes; Felzenszwalb, Israel; Silva, Manuela da

doi:10.3395/2317-269x.00595

Cited by 2 publications

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“…In the environment, white rot fungi synthesize oxidoreductases, e.g., peroxidases, which facilitate the biodegradation of the lignocellulose complex of plant biomass. Due to their wide range of substrates, fungal peroxidases can decompose compounds with an aromatic structure, e.g., pesticides, melanoidin, industrial dyes, post-industrial lignin, personal care products, and pharmaceuticals [8,14,[16][17][18][19][20][21][22][23].…”

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confidence: 99%

Enhanced Efficiency of the Removal of Cytostatic Anthracycline Drugs Using Immobilized Mycelium of Bjerkandera adusta CCBAS 930

Rybczyńska‐Tkaczyk

2021

Molecules

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The aim of this study was to evaluate the bioremoval of anthracycline antibiotics (daunomycin-DNR, doxorubicin–DOX, and mitoxantrone-MTX) by immobilized mycelium of B. adusta CCBAS 930. The activity of oxidoreductases: versatile peroxidases (VP), superoxide dismutase (SOD), catalase (CAT), and glucose oxidase (GOX), and the levels of phenolic compounds (PhC) and free radicals (SOR) were determined during the biotransformation of anthracyclines by B. adusta strain CCBAS 930. Moreover, the phytotoxicity (Lepidium sativum L.), biotoxicity (MARA assay), and genotoxicity of anthracyclines were evaluated after biological treatment. After 120 h, more than 90% of anthracyclines were removed by the immobilized mycelium of B. adusta CCBAS 930. The effective biotransformation of anthracyclines was correlated with detoxification and reduced genotoxicity.

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