DXAGE 2.0 — adult age at death estimation using bone loss in the proximal femur and the second metacarpal

Curate, Francisco; Navega, David; Cunha, Eugénia; Coelho, João d’Oliveira

doi:10.1007/s00414-022-02840-y

Cited by 7 publications

(12 citation statements)

References 113 publications

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“…Notwithstanding, the method presented here performs slightly worse than recent methodological routines that rely on advanced mathematical approaches, e.g., [3,7,62], including those that are also based on medical imaging of the proximal femur [9,15]. Interestingly, and contrarywise to what was observed in densitometric studies of the proximal femur, the eigenfemora approach is more accurate in the age estimation of male individuals.…”

Section: Discussionmentioning

confidence: 56%

“…Interestingly, and contrarywise to what was observed in densitometric studies of the proximal femur, the eigenfemora approach is more accurate in the age estimation of male individuals. This highlights a potential benefit for age estimation in male individuals through the eigenfemora models when compared with age prediction through densitometry, e.g., [9,15]. In fact, bone decline with age at the proximal femur is more obvious in female individuals -and that seems to be a general trend in different populations [15,22,23,40,42].…”

Section: Discussionmentioning

confidence: 94%

“…Being the bigger and one of the more robust bones of the human skeleton, its preservation is often better than other parts of skeleton [51]. In fact, the femur, and particularly the proximal region, is of paramount significance for the assessment of different parameters of the biological profile [52][53][54][55][56], including age at death [9,15,40,42,57].…”

Section: Discussionmentioning

confidence: 99%

“…Age-related bone loss occurs in all populations, with age-specific bone remodeling taking place in different skeletal regions at dissimilar rates [13][14][15][16]. Trabecular bone has more surface per unit of bone volume than cortical bone, and accelerated remodeling initially stimulates a more pronounced cancellous bone loss as opposed to cortical bone loss [17].…”

Section: Introductionmentioning

confidence: 99%

“…Proximal femur bone loss has also been used to systematize standards for age at death estimation in adult skeletons [9,15,24,25,35,[40][41][42]. These studies suggest that the proximal femur is reliable to estimate age at death and average to excellent results have been claimed.…”

Section: Introductionmentioning

confidence: 99%

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Eigenfemora – Age at Death Estimation in the Proximal Femur through an Image Processing Approach

Navega,

Ferreira,

Curate

2023

Preprint

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Estimating age at death is essential to establish a biological profile from human skeletal remains in both forensic and archeological settings. Imaging studies of skeletal age changes in adults have described metamorphosis of trabecular bone structure and bone loss in the proximal femur , as well as changes in morphology during different stages of life. This study aims to assess the utility of a digital representation of conventional X-ray films of the proximal femur for the estimation of age at death in a sample of 91 adult individuals (47 females and 44 males) of the Coimbra Identified Skeletal Collection. The proposed approach showed a root mean squared error (RMSE) of 17.32 years (and mean absolute error of 13.47 years) for females and an RMSE of 14.06 years (mean absolute error of 11.08 years) for males. The main advantage of this approach is the consistency in the feature detection and extraction, as X-ray images projected on the femora space will always produce the same set features to be analyzed for age estimation while more traditional methods rely heavily on operator experience which can lead to inconsistent age estimates among experts.

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