“DVT” of the Heart

Pothineni, Naga Venkata K.; Bahia, Amit; Gobal, Freij; Ahmed, Zubair; Uretsky, Barry F.; Hakeem, Abdul

doi:10.1016/j.jcin.2015.03.036

Cited by 3 publications

(1 citation statement)

References 2 publications

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“…SVG thrombosis is called the “deep vein thrombosis” of the heart and its possible pathophysiology is assumed to be the same as that of deep vein thrombosis [6]; therefore, novel oral anticoagulants (NOACs) were effective for SVG thrombosis, as shown in the present case. In addition, the resolution of the thrombus with apixaban was rapid (within just 3 weeks).…”

Section: Discussionmentioning

confidence: 85%

Apixaban for the treatment of saphenous vein graft thrombosis presenting as unstable angina: a case report

2017

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BackgroundSaphenous vein graft thrombosis can present as unstable angina. However, percutaneous coronary intervention for saphenous vein graft lesions poses a high risk of slow flow related to the procedure. Here we present the utilization of the novel oral anticoagulant, apixaban, in the treatment of unstable angina with extensive saphenous vein graft thrombus, leading to considerable thrombus resolution and eliminating the need of percutaneous coronary intervention.Case presentationA 72-year-old man with 3-vessel coronary artery bypass graft surgery using a saphenous vein graft and a left internal mammary artery, performed 25 years earlier, presented at our hospital with recurrent chest tightness. The echocardiography showed regional hypokinesis of the post-lateral wall with moderate left ventricular dysfunction, which had not been previously confirmed. Coronary angiography showed obstruction of the saphenous vein graft with a large thrombus burden. The left internal mammary artery was patent and other natives were the same as they had been 3 years ago. He was diagnosed with unstable angina due to acute saphenous vein graft thrombosis. Instead of percutaneous coronary intervention, he was treated with apixaban 5 mg twice a day. The angiography 3 weeks after starting apixaban showed considerable resolution of the thrombus and opening of the saphenous vein graft.ConclusionsApixaban could become a viable treatment option for acute saphenous vein graft thrombosis.Electronic supplementary materialThe online version of this article (doi:10.1186/s12959-017-0133-5) contains supplementary material, which is available to authorized users.

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Section: Discussionmentioning

confidence: 85%

Apixaban for the treatment of saphenous vein graft thrombosis presenting as unstable angina: a case report

2017

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Diffuse saphenous vein graft thrombosis: resolution after one month of apixaban and dual antiplatelet therapy

Dickson

Taleb²,

Wiernek³

et al. 2020

Coronary Artery Disease

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Successful Treatment of a Huge Thrombotic Saphenous Vein Graft Occlusion with Aspiration Thrombectomy: A Case Report

Akçay

2020

JTHC

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Saphenous vein grafts (SVGs) are widely used conduits for the surgical revascularization of coronary arteries, but they are associated with poor long-term patency rates. Acute SVG thromboses often present as acute coronary syndrome and have an extensive atherosclerotic and thrombotic burden. Percutaneous coronary intervention (PCI) is the first treatment option; however, it carries a high risk of distal embolization, no-reflow, and periprocedural myocardial infarction. Reducing the thrombus burden and preventing distal embolization during PCI can be achieved by using some pharmacological strategies (e.g., glycoprotein IIb/IIIa antagonists) and devices (e.g., thrombectomy and filter devices). There are yet no better therapeutic options for patients undergoing PCI of SVG occlusions. Here, we introduce a 52-year-old male patient admitted with a typical acute chest pain of 1 hour’s duration. Electrocardiography showed signs of acute inferoposterior myocardial infarction. A thrombotic SVG occlusion was detected in primary PCI, and a huge thrombus content was aspirated. After the thrombus aspiration with stent implantation, the chest pain was relieved and the ST-segment elevation was improved. The patient has been followed without any symptoms for 10 months.

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“DVT” of the Heart

Cited by 3 publications

References 2 publications

Apixaban for the treatment of saphenous vein graft thrombosis presenting as unstable angina: a case report

Apixaban for the treatment of saphenous vein graft thrombosis presenting as unstable angina: a case report

Diffuse saphenous vein graft thrombosis: resolution after one month of apixaban and dual antiplatelet therapy

Successful Treatment of a Huge Thrombotic Saphenous Vein Graft Occlusion with Aspiration Thrombectomy: A Case Report

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