Duration of treadmill exercise testing combined with QRS score predicts adverse cardiac outcome at long-term follow-up

Abstract

This study shows that a new index termed the M score, which incorporates QRS score and exercise duration, predicts mortality and occurrence of myocardial infarction at long-term follow-up of high-risk individuals, independently of TET-induced ST-segment changes.

Cardiorespiratory fitness is positively correlated with cerebral white matter integrity in healthy seniors

“…However, total treadmill exercise time and one minute heart rate recovery are also strong predictors of cardiac related events (Ekelund et al, 1988; Hsich et al, 2009) (Cole et al, 1999; Nishime et al, 2000; Watanabe et al, 2001). In addition, the prognostic accuracy of cardiac-related events increases when these physiological responses are combined in a single fitness score or index (Gulati et al, 2005; Mark et al, 1987; Michaelides et al, 2009; Myers et al, 2008; Shaw et al, 1998). Consequently, the combined use of multiple measures of CRF (VO 2 peak, total time on treadmill, and 1-minute HR recovery) are thought to represent a more comprehensive metric of CRF that reflects functional aerobic capacity and individual differences in physical activity (D'Amore and Mora, 2006).…”

The impact of novel exercise criteria and indices for the diagnostic and prognostic ability of exercise testing

“…M score completes all the aforementioned prognostic modalities, since, according to our results, it is significantly, independently, and inversely associated with the risk of myocardial infarction and/or death. In fact, it has also been established that the lower quartile of the M score values (values b 5.758) are independently associated with adverse prognosis [35] (Table 2).…”

“…It was shown that "Athens score" has proved to be an important alternative in estimating the heart patients and defining their prognosis [34]. Quite recently, in a continuous effort to improve the clinical value of ET, a novel prognostic index was invented, called "M score" (Michaelides score) [35]. M score is a clear number and is calculated by adding the value of the "Athens QRS score" with total exercise duration during ET (in minutes): M score = Athens QRS Score + exercise time.…”