Duration of Secretion of Bacteriostatic Drugs in Milk. I. Penicillin, Following Oral and Parenteral Administration

Etiology and prevention of ruminant bloat

“…The oral administration of a single dose of 10.0 gm. of procaine penicillin to lactating «ows produced de tectable amounts of penicillin in the milk up to 86 hr, after adminis tration (Cannon et al, 1962), However, no detectable residue was found in the milk 96 hr, after administration.…”

“…How ever, feed consuBçtion and milk production returned to normal within a few days. Cannon et (1962) rQ)orted that cows i6ich had been fed 10,000,000 units of procaine penicillin in a single dose exhibited syicptoms of physiological disturbances including severe scouring, loss of appetite, reduction of milk yield and an increase in the fat percent age of the milk.…”

Influência da mastite na ocorrência de resíduos de antimicrobianos no leite

“…Dentre os principais fatores que afetam a taxa de excreção e a presença de antibióticos no leite, destacam-se: a quantidade de leite produzida pelo animal e o intervalo de tempo entre o tratamento e a ordenha (MARTH e ELLICKSON, 1959), os tipos de antibióticos e veículos utilizados, as vias de administração e as doses administradas (CANNON et al, 1972.…”