Duration of Oral Contraceptives Use and Risk of Development of Dyslipidemia among Women in Dhaka City

Abstract

Background: Duration of oral contraceptive use is an important issue for the development of dyslipidemia among women. Objective: The purpose of the present study was to see the duration of use of OCP and the development of dyslipidemia among the women. (1) year. Women using low-dose OC pill for more than one year were considered as cases group while women not using low-dose oral contraceptive pill were taken as control group of the study. Lipid profiles were performed in the laboratory in the fasting state from blood. Result: A total of 80 subjects were recruited for this study of which 40 women in case group and the rest 40 women were in control group. Duration of contraceptive use and serum lipids profiles were recorded. Level of serum total cholesterol, serum triglyceride, and serum LDL were significantly higher among the contraceptive users of > 5 years duration than those among 5 or < 5 years duration (p < 0.001). However, serum HDL level was low among both users and non-users (p=0.556). The risk of developing dyslipidaemia in women using low-dose oral contraceptive was more than 3-fold higher than that in non-users. Conclusion: In conclusion the greater the duration of oral contraceptive use the higher is the chance of dyslipidaemia.

Effect of Oral Contraceptives on Lipid Profile in Premenopausal Indian Women

“…In one of the study 28 it was shown that greater the duration of oral contraceptive use the higher is the chance of dyslipidaemia.…”