Duration of disease influences survival to discharge of<scp>T</scp>horoughbred mares with surgically treated large colon volvulus

Hackett, Eileen S.; Embertson, R. M.; Hopper, S. A.; Woodie, J. Brett; Ruggles, Alan J.

doi:10.1111/evj.12358

Cited by 37 publications

(51 citation statements)

References 32 publications

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“…Increased PCV at admission was associated with nonsurvival in horses with LCV, as was the case in other studies . Increased PCV is reflective of the duration of the colic and the degree of systemic compromise of the horse .…”

Section: Discussionsupporting

confidence: 76%

“…Strangulating large colon volvulus (LCV) is a serious manifestation of colic that has been classically associated with mortality rates of 35% to 86% . However, an 88% survival to discharge has been described that was attributed to early recognition and prompt surgical intervention . Despite this improvement, no objective intraoperative measurement to determine colonic viability exists in cases in which prolonged ischemia has occurred.…”

Section: Introductionmentioning

confidence: 99%

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Prognostic value of colonic and peripheral venous lactate measurements in horses with large colon volvulus

et al. 2020

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Objective To determine the prognostic value of (1) colonic venous lactate or peripheral lactate values obtained before and after manual correction of a large colon volvulus and (2) a combination of variables including pelvic flexure biopsy. Study design Prospective clinical study. Animals Forty adult horses in which large colon volvulus was diagnosed intraoperatively. Methods Colonic venous, peripheral venous, and arterial blood samples were collected to measure lactate values before and after manual correction. Mucosal biopsy samples were obtained in cases that underwent enterotomy or colonic resection and anastomosis. Interstitium to crypt (I:C) ratio and hemorrhage scores were measured. Optimal cutoff values were determined by receiver operator curve analysis, and associations between variables and short‐term outcome were determined by univariable regression. Short‐term survival was defined as horses being discharged from the hospital. P ≤ .05 was considered significant. Results No association was found between colonic venous lactate values before (P = .011) or after (P = .201) manual correction of large colon volvulus and determination of short‐term outcome. Peripheral venous lactate at admission ≥3.2 mmol/L and after manual correction ≥5 mmol/L, arterial lactate postmanual correction ≥3.53 mmol/L, and histomorphometric measurements of mucosal hemorrhage ≥3 and I:C ratio > 1 were associated with poor short‐term outcome. Conclusion Peripheral lactate values, histomorphometric measures of I:C ratio, and hemorrhage score provided prognostic information that could help guide recommendations made to owners. Clinical significance Peripheral lactate values after manual correction provide important intraoperative diagnostic information to assist in predicting case outcome in the operative and immediately postoperative period.

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Section: Discussionsupporting

confidence: 76%

Section: Introductionmentioning

confidence: 99%

Prognostic value of colonic and peripheral venous lactate measurements in horses with large colon volvulus

et al. 2020

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“…The location of common colon lesions, namely large colon volvulus, might also contribute to disease morbidity . Both anastomotic methods utilized in the present report were performed at comparable locations, removing similar amounts of the colon.…”

Section: Discussionmentioning

confidence: 95%

“…Large colon‐related diseases are commonly associated with colic in horses and account for more than one‐third of horses undergoing exploratory celiotomy for gastrointestinal pain . Colectomy is performed for salvage in cases with severe disease and intestinal necrosis, such as in horses with strangulating large colon volvulus .…”

Section: Introductionmentioning

confidence: 99%

Technique‐associated outcomes in horses following large colon resection

Pezzanite

Hackett

2017

Veterinary Surgery

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“…; Hackett et al . ). Foals appear prone to post‐operative intra‐abdominal adhesions, a need for repeat laparotomy and a decrease in long‐term survival (Cable et al .…”

Section: Discussionmentioning

confidence: 97%

Volvulus of the large colon in a neonatal foal

Preez

Trope

Owens

et al. 2017

Equine Veterinary Education

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Summary A one‐day‐old Thoroughbred colt foal was presented for assessment of abdominal pain and reduced urine output. Physical examination of the foal revealed marked abdominal distension, mild tachycardia, tachypnoea and congested mucous membranes. A marked anechoic peritoneal effusion, intestinal hypomotility and mural thickening of the large colon were detected sonographically. Serosanguinous fluid was obtained by abdominocentesis. After haemodynamic stabilisation, the foal underwent general anaesthesia and exploratory laparotomy and a 720° volvulus of the large colon at the sternal and diaphragmatic flexures was identified. After correction of the volvulus, the intraoperative findings were consistent with nonviability of the affected portion of the colon. The owner declined partial colon resection and elected for euthanasia of the foal. Although rare in neonatal foals, large colon volvulus should be considered in foals with signs of abdominal pain, abdominal distension and ultrasonographic findings of colonic mural thickening and luminal distension.

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Duration of disease influences survival to discharge ofThoroughbred mares with surgically treated large colon volvulus

Cited by 37 publications

References 32 publications

Prognostic value of colonic and peripheral venous lactate measurements in horses with large colon volvulus

Prognostic value of colonic and peripheral venous lactate measurements in horses with large colon volvulus

Technique‐associated outcomes in horses following large colon resection

Volvulus of the large colon in a neonatal foal

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