Duration of antibacterial treatment for uncomplicated urinary tract infection in women

Milo, Gai; Katchman, Eugene; Paul, Mical; Christiaens, Thierry; Bærheim, Anders; Leibovici, Leonard

doi:10.1002/14651858.cd004682.pub2

Cited by 89 publications

(47 citation statements)

References 60 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…6,7 However, in non-pregnant women with moderate-to-severe symptoms, a 3-day course of trimethoprim (200 mg twice daily) or nitrofurantoin (50-100 mg four times daily) is recommended and can shorten the duration of symptoms by 1-2 days. 7,8 The modern patient-centred NHS is committed to ensuring better, local, faster health care, putting the interests of patients at the centre of reforms thereby offering greater choice in how, when, and where to access healthcare services. 9 Community pharmacies provide convenient access to a qualified healthcare professional without an appointment and routinely advise on minor ailments, including UTIs.…”

mentioning

confidence: 99%

Antibiotic treatment of urinary tract infection by community pharmacists: a cross-sectional study

et al. 2013

View full text Add to dashboard Cite

mentioning

confidence: 99%

Antibiotic treatment of urinary tract infection by community pharmacists: a cross-sectional study

et al. 2013

View full text Add to dashboard Cite

“…1,2 Research based on patients' experiences, however, mentions a broad range of symptoms, 3,4 and although UTI is the most common infectious disease in adult women, the course of these symptoms is not well documented. Correct information about the symptoms and their average duration is important to reassure the patient and to avoid unnecessary reconsultation, referrals, or changes in treatment, such as a switch to broad-spectrum antibiotics.…”

mentioning

confidence: 99%

Cystitis: Symptomatology in Women with Suspected Uncomplicated Urinary Tract Infection

Heytens

Sutter

Backer

et al. 2011

Journal of Women's Health

Self Cite

View full text Add to dashboard Cite

Background: Although cystitis in women is very common in general practice, its evolution in symptoms has not been clearly studied. Qualitative research has pointed to other than the classic symptomatology. Methods: This was a prospective observational study of the symptomatology at presentation and the evolution of the symptoms in treated women with suspected uncomplicated urinary tract infection (UTI). Women consulting their general practitioner (GP) for dysuria, urgency, or frequency produced a urine sample (for bacteriologic processing) and kept a diary until the end of the symptoms. Exclusion criteria included complaints > 1 week, fever, vaginal discharge, and known pathology. Results: Of the 300 asked to participate, 148 (49%) returned the diary. Although none of the patients developed acute pyelonephritis, a substantial number of the women had such complaints as feeling feverish (33% in culture-positive group, 38% in culture-negative group), back pains (44% vs. 56%), and feeling weak and tired (71% vs. 65%). Differences between the culture-positive and culture-negative groups were not statistically significant except for the duration of symptoms, which was shorter in the culture-positive group (4 vs. 6 days). More severe symptoms at inclusion were correlated with a longer duration of these symptoms. Conclusions: The spectrum of complaints in women with suspected uncomplicated UTI is broad and comprises a number of symptoms usually associated with an upper UTI. The occurrence of these symptoms should not automatically prompt GPs to prescribe broad-spectrum antibiotics. Moreover, the duration of symptoms exceeding the recommended duration of antibiotic therapy does not indicate therapy failure and, thus, the need for changing antibiotic therapy.

show abstract

“…19,20 Short course antibiotic treatment (3-6 days) is as effective as long course (7-14 days) for the symptomatic treatment of uncomplicated infections, although longer courses are more effective at bacterial eradication. 21,22 In women with rUTI associated with sexual intercourse postcoital prophylaxis is as effective as low dose prophylaxis. 20 Trimethoprim, co-trimoxazole, nitrofurantoin, cephalexin, or fluoroquinolone (ciprofloxacin) are equally as effective for both short course treatment and low dose prophylaxis in eradication of S92 | symptomatic infections.…”

Section: And Resistancementioning

confidence: 99%

“…Whilst success rates of 84% to 100% have been claimed for 3 and 14 day treatments, 32 others have reported microbiological and symptomatic failure in up to 37% of patients within 14 weeks of treatment. 22 Among healthy young women who suffer from their first UTI, the risk of recurrence within 6 months is 24%. If they have a history of one or more infections, the risk of recurrence rises to 70% in that same year.…”

Section: In Chronic Utimentioning

confidence: 99%

How can we improve investigation, prevention and treatment for recurrent urinary tract infections – ICI‐RS 2018

Harding

Rantell

Cardozo

et al. 2019

Neurourology and Urodynamics

View full text Add to dashboard Cite

Background: Recurrent urinary tract infection (rUTI) is a chronic conditionand has a significant impact on health-related quality of life. The commonly used definition for rUTI is greater than three episodes in a year or more than two in 6 months. Current diagnostic methods have been used worldwide for over five decades, despite well evidenced criticism. Enhanced culture techniques demonstrate that the microbiome of the bladder is far more complex than previously thought and begs a reappraisal of our current testing. Treatment of rUTI is based on a small number of antibiotic trials with some evidence showing a reduction in the number of positive cultures, but one must be cautious in interpreting the results and weigh against the risk of generation of antimicrobial resistance (AMR).Aim: The International Consultation on Incontinence-Research Society think tank reviewed the literature with a view to improving investigation, prevention and treatment of rUTI. Methods: A multidisciplinary team of experts were invited to present evidence regarding the current diagnostic methods, recent advances related to bladder biome mapping and current treatment strategies, including antibiotic and nonantibiotic options. Current guidelines regarding antibiotic stewardship and concerns regarding AMR were discussed. Discussion: Outcome of the think tank discussions are summarised with a set of recommendations to inform future research. Particular consideration is given to bacterial survival in the bladder after treatment as well as defects in urothelial barrier function which may play a significant part in the failure to eradicate UTI. K E Y W O R D S antimicrobial resistance, urinary tract infection Neurourology and Urodynamics. 2019;38:S90-S97. wileyonlinelibrary.com/journal/nau S90 |

show abstract

Duration of antibacterial treatment for uncomplicated urinary tract infection in women

Abstract: Analysis 01.06. Comparison 01 Three days versus 5-10 day antibiotic therapy, Outcome 06 Short-term bacteriological failure by antiboitic class (same drug

Cited by 89 publications

References 60 publications

Antibiotic treatment of urinary tract infection by community pharmacists: a cross-sectional study

Antibiotic treatment of urinary tract infection by community pharmacists: a cross-sectional study

Cystitis: Symptomatology in Women with Suspected Uncomplicated Urinary Tract Infection

How can we improve investigation, prevention and treatment for recurrent urinary tract infections – ICI‐RS 2018

Contact Info

Product

Resources

About