Background
During an epidural blood patch, we inject blood until the patient describes
mild back pressure, often leading to injection of more than 20 mL of blood. We undertook
this study to measure the epidural pressures generated during an epidural blood patch
and to identify the impact of volume on epidural elastance in obstetric patients.
Methods
This study was performed in postpartum patients who presented for an epidural
blood patch with symptoms consistent with a postdural puncture headache. After
identification of the epidural space using loss of resistance to air or saline, we
measured static epidural pressure after each 5-mL injection of blood. Models were then
fitted to the data and the epidural elastance and compliance calculated.
Results
Eighteen blood patches were performed on 17 patients. The mean final volume
injected was 18.9 ± 7.8 mL [range 6 to 38 mL]. The mean final pressure generated
was 13.1 ± 13.4 mmHg [range 2 to 56 mmHg]. A curvilinear relationship existed
between volume injected and pressure, which was described by two models: (1) pressure =
0.0254 × (mL injected)2 + 0.0297 × mL, or (2) pressure =
0.0679 × mL1.742. The value for r2 was approximately 0.57
for both models. We found no correlation between the final pressure generated and the
success of the EBP.
Conclusions
We found a curvilinear relationship between the volume of blood injected during
an epidural blood patch and the pressure generated in the epidural space. However, there
was a large variation in both the volume of blood and the epidural pressure generated.
The clinical importance of this finding is not known. A larger study would be required
to demonstrate whether pressure is a predictor of success.