Dural mural cells paint an anti-inflammatory picture
Nicole C. Lummis,
Benjamin D. Gastfriend,
Richard Daneman
Abstract:Mural cells directly contact macrophages in the dural layer of the meninges to suppress pro-inflammatory phenotypes, including antigen presentation and lymphocyte differentiation. These mechanisms represent new targets for modulating CNS immune surveillance and pathological inflammation (Min et al. 2024. J. Exp. Med.https://doi.org/10.1084/jem.20230326).
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