Durable spontaneous regression of lung metastases from renal cell carcinoma after incomplete use of multiple kinase inhibitor sorafenib

Hegde, Upendra P.; Patel, Vatsal; Kaloudis, Electra

doi:10.1111/iju.12011

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Patterns Of Metastases In Rcc1

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“…There are several sites of metastases that are associated with more favorable prognoses. Multiple anecdotal reports exist documenting regression of lung metastases following either brief local or systemic therapy for mRCC, and broadly, patients with lung-only metastases are thought to carry a favorable prognosis [39] , [40] , [41] . Interestingly, pancreatic metastases are also thought to confer a favorable prognosis.…”

Section: Patterns Of Metastases In Rccmentioning

confidence: 99%

Metastasis in renal cell carcinoma: Biology and implications for therapy

Gong

Maia²,

Dizman

et al. 2016

Asian Journal of Urology

113

121

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Although multiple advances have been made in systemic therapy for renal cell carcinoma (RCC), metastatic RCC remains incurable. In the current review, we focus on the underlying biology of RCC and plausible mechanisms of metastasis. We further outline evolving strategies to combat metastasis through adjuvant therapy. Finally, we discuss clinical patterns of metastasis in RCC and how distinct systemic therapy approaches may be considered based on the anatomic location of metastasis.

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Section: Patterns Of Metastases In Rccmentioning

confidence: 99%