Durable polymer versus bioabsorbable polymer drug eluting stents in right coronary artery chronic total occlusions: Eighteen months (median) results of a single-center experience

Abstract

Objective: There are a few data regarding the long-term clinical outcomes of durable polymer (DP) drug-eluting stents (DES) versus bio absorbable polymer (BP) drug-eluting stents treatment in patients with right coronary artery (RCA) chronic total occlusion (CTO). The aim of this study was to compare the clinical outcomes of these stents according to their polymer-based difference. Methods:Between June 2013 and August 2016, 66 RCA CTO patients enrolled in the study. Fortyseven patients with successful CTO recanalization of RCA via ante grade or retrograde approach using either DP (n=25) and BP (n=22) were scheduled for 6, 12, and 18 months clinical follow-up. Primary clinical outcomes were cardiac death and major adverse cardiac events (MACE).Results: RCA CTO success rate was 71%. There was no difference in Japanese-CTO (JCTO) scores between two groups. Total stent length was longer in BP group, and it was statistically significant (p=0.015). The incidence of cardiac death was not significant between the two groups. After propensity score matching, TVR rates were 12.0% for DP group and 9.1% for BP group at the end of the 18th month (hazard ratio [HR] 182-4.718; p=0.927). Conclusion:This study shows that the efficacy of BP-DES is comparable to that second-generation DP-DES treatment for RCA CTO over 18-month follow-up.

Interventional Cardiology: Volume 9, Issue 6

“…The biodegradable polymer drug eluting stents (BP-DES) developed to overcome the limitations associated with the first generation durable polymer DES (DP-DES), have not exhibited consistent results in clinical trials. Cicek [4] compared the long-term clinical outcomes of DP-DES with BP-DES in patients suffering from right coronary artery (RCA) chronic total occlusion (CTO). The results of the study revealed that the efficacy of BP-DES is comparable to that of DP-DES.…”

“…Chu et al [3], tested the accuracy of a newly developed algorithm for a 12-lead electrocardiogram which was directed at identifying the accessory pathways (APs) in the WolffParkinson-White (WPW) syndrome. Cicek [4] compared the long-term clinical outcomes of durable polymer drug-eluting stent (DP-DES) with biodegradable polymer drug eluting stents (BP-DES) in patients suffering from right coronary artery (RCA) chronic total occlusion (CTO). Carini et al [5], described a case of an aorto-pulmonary window identified during a surgery for Type A interrupted aortic arch, which was repaired without any hindrance.…”