Durability and stability of antimicrobial coated surfaces

Abstract

Antimicrobial surface coating of i.e. medical devices could contribute to infection prevention and reduction of hospital acquired infections (HAI). Recent studies showed a significant reduction in the microbial contamination of antimicrobial coated surfaces in clinical setups. Nevertheless, there are only few publications available that deal with the durability and stability of these coatings under routine clinical conditions. In this work different antimicrobial coating compositions were tested on different surfaces for their durability and remaining antimicrobial activity. Our results show that the durability and stability of a subsequent applied antimicrobial coating is strongly dependent on the chemical formulation of the coating and also the underlying surface condition. Whereas we could still detect remaining antimicrobial coating and activity on some samples after repeated abrasion testing, some other samples lost their coating and activity after only a few abrasion cycles. Interestingly the integrated antimicrobial substance in the 3-D printed samples showed strong antimicrobial activity even after rough treatment of the surfaces (brushing, scratching).

Critical analysis of methods to determine growth, control and analysis of biofilms for potential non-submerged antibiofilm surfaces and coatings

“…repeated touch, cleaning regimes), does not form part of the standard methodology described in many antibiofilm surfaces studies (although it is not totally absent from the literature [e.g. 70]), with more recognition of its importance in antimicrobial surfaces literature [ 129 ] and US EPA guidance ‘Interim method for evaluating the efficacy of antimicrobial surface coatings’. Similarly, during antibiofilm efficacy testing, understanding biofilm regrowth after quantification/removal could be another indicator of antibiofilm efficacy.…”

Mechanical and Biological Properties of Titanium and Its Alloys for Oral Implant with Preparation Techniques: A Review

“…It develops from healthy peri-implant mucosa around osseointegrated dental implants after accumulating bacterial biofilms [99]. To solve this problem, antimicrobial coatings have been developed to restrain and forestall bacterial infections [100][101][102]. The titanium surface must be treated by adding material or agents in coatings to forestall bacterial colonisation.…”

Antiviral and Antibacterial 3D-Printed Products Functionalised with Poly(hexamethylene biguanide)

“…With the advancement in nanoscience, antimicrobial spray coatings for biomedical applications based on polymers or nanocomposites are being antimicrobial spray coatings for biomedical applications based on polymers or nanocomposites are being developed that have compelling antimicrobial performances [6][7][8][9][10][11][12]. Nevertheless, the long-term efficacy, i.e., durability of antimicrobial coatings applied to different surfaces via chemical spraying, is the main concern of the end users [13,14]. In general, many coatings available on the market have been proven to last between 3 and 6 months under testing conditions in laboratories.…”