Duplication and divergence of Sox genes in spiders

Paese, Christian Louis Bonatto; Leite, Daniel J.; Schoenauer, Anna; McGregor, Alistair P.; Russell, Steven

doi:10.1101/212647

Cited by 7 publications

(19 citation statements)

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“…Here we show that, while Dichaete is not involved in spider segmentation (21), the closely related SoxB gene, Sox21b-1 , regulates formation of both prosomal and opisthosomal segments. In the prosoma Sox21b-1 has a gap gene role and is required for the specification of L1-L4 segments (Fig.…”

Section: Discussionmentioning

confidence: 77%

“…We previously identified and assayed the expression of the complement of Sox genes in the genome of the spider P. tepidariorum (21). Our phylogenetic analysis indicates that P. tepidariorum Sox21b-1 and its paralog Sox21b-2 are members of the Sox group B, closely related to the Drosophila Dichaete and Sox21b genes (Fig.…”

Section: Resultsmentioning

confidence: 99%

“…S1). In insects (22, 23), Dichaete, Sox21a and Sox21b are clustered in the genome, however, both Sox21b paralogs are dispersed in the spider genome (21). This suggests that Sox21b-1 and Sox21b-2 possibly arose from the WGD event in the ancestor of arachnopulmonates (24), rather than by a more recent tandem duplication (20) (Fig.…”

Section: Resultsmentioning

confidence: 99%

“…1F-H). Later in development, the expression of Sox21b-1 resembles that of SoxNeuro ( SoxN ), another Group B Sox gene (21). This expression is similar to that of both SoxN and Dichaete in D. melanogaster , which are expressed in neuroblasts of the neuroectoderm and then differentiating neurons in the ventral nerve cord (22) (Fig.…”

Section: Resultsmentioning

confidence: 99%

“…We recently described the discovery of 14 Sox genes in the genome of the spider P. tepidariorum (21) and that several of the spider Sox genes are represented by multiple copies likely produced during the whole genome duplication (WGD) in the lineage leading to this arachnid (21). Interestingly, while Dichaete is not expressed in a pattern consistent with a role in segmentation (21), we found that the closely related SoxB gene, Sox21b-1 , is expressed in both the prosoma and opisthosoma before and during segmentation (21). Here we report that in P. tepidariorum , Sox21b-1 , regulates both prosomal and opisthosomal segmentation.…”

Section: Introductionmentioning

confidence: 99%

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A SoxB gene acts as an anterior gap gene and regulates posterior segment addition in the spiderParasteatoda tepidariorum

Paese

Schoenauer

Leite

et al. 2018

Preprint

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SummaryThe Sox gene family encode a set of highly conserved HMG domain transcription factors that regulate many key processes during metazoan embryogenesis. In insects, the SoxB gene Dichaete is the only Sox gene known to be involved in embryonic segmentation. To determine if similar mechanisms are used in other arthropods, we investigated the role of Sox genes during segmentation in the spider Parasteatoda tepidariorum. While Dichaete does not appear to be involved in spider segmentation, RNAi knockdown of the closely related Sox21b-1 gene results in a gap like phenotype in the developing prosoma and also perturbs the sequential addition of opisthosomal segments. We show that this is in part due to a role for Sox21b-1 in regulating the expression of Wnt8 and influencing Delta-Notch signalling during the formation of the segment addition zone. Thus, we have found that two different mechanisms for segmentation in a non-mandibulate arthropod are regulated by a Group B Sox gene. Our work provides new insights into the function of an important and conserved gene family across arthropods, and the evolution of the regulation of segmentation in these animals.

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Section: Discussionmentioning

confidence: 77%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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A SoxB gene acts as an anterior gap gene and regulates posterior segment addition in the spiderParasteatoda tepidariorum

Paese

Schoenauer

Leite

et al. 2018

Preprint

Self Cite

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How spiders make their eyes: Systemic paralogy and function of retinal determination network homologs in arachnids

Gainett

Ballesteros

Kanzler

et al. 2020

Preprint

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17 18 Arachnids are important components of cave ecosystems and display many examples of 19 troglomorphisms, such as blindness, depigmentation, and elongate appendages. Little is 20 known about how the eyes of arachnids are specified genetically, let alone the mechanisms 21 for eye reduction and loss in troglomorphic arachnids. Additionally, paralogy of Retinal 22 Parasteatoda tepidariorum. We provide functional evidence that one of these paralogs, sine 35 oculis/Six1 A (soA), is necessary for the development of all arachnid eye types. Our results 36 support the conservation of at least one RDGN component across Arthropoda and establish a 37 framework for investigating the role of gene duplications in arachnid eye diversity. 38 39 Keywords: cave blindness | sine oculis | Six1 | Parasteatoda tepidariorum | Amblypygi | 40 RNAi 41 42

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The Molecular Mechanism of Embryonic Development in Decapod Crustaceans

Farhadi,

Zhao,

Tan

2024

Reviews in Aquaculture

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In recent decades, the decapod aquaculture industry has grown significantly in many parts of the world. Despite this progress, production levels still fall short of market demands, indicating a need for further efforts to increase the production. Investigations into the molecular mechanisms underlying embryonic development in decapods provide valuable insights into the complex embryonic development processes of this economically and ecologically important animal group. In this review, we explore the molecular mechanisms underlying decapod embryonic development, focusing on key genes, signaling pathways, and microRNAs (miRNAs) involved in the embryogenesis. Numerous genes have been identified that regulate various aspects of embryogenesis including egg activation, maternal‐to‐zygotic transition (MZT), mesoderm development, segmentation, nervous system development, sex determination, germline development, and exoskeleton formation. We also discuss the pivotal role of signaling pathways such as Hedgehog, Wnt, Notch, MAPK, TGF‐β, Jak‐STAT, VEGF, and Ecdysteroid in the regulation of embryogenesis. Additionally, this review identifies current research gaps in decapod embryogenesis and proposes directions for future investigation. This review is anticipated to be especially beneficial for researchers delving into the molecular mechanisms driving embryonic development in decapods.

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Duplication and divergence of Sox genes in spiders

Abstract: Background

Cited by 7 publications

References 70 publications

A SoxB gene acts as an anterior gap gene and regulates posterior segment addition in the spiderParasteatoda tepidariorum

A SoxB gene acts as an anterior gap gene and regulates posterior segment addition in the spiderParasteatoda tepidariorum

How spiders make their eyes: Systemic paralogy and function of retinal determination network homologs in arachnids

The Molecular Mechanism of Embryonic Development in Decapod Crustaceans

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