Duodenal Switch: An Effective Therapy for Morbid Obesity - Intermediate Results

Baltasar, Aniceto; Bou, Rafael; Bengochea, Marcelo; Arlandis, Francisco; Escrivá, Carlos; Miró, Javier; Martı́nez, R.; Pérez, Nieves

doi:10.1381/096089201321454114

Cited by 91 publications

(29 citation statements)

References 10 publications

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“…However, we believe that gastric capacity is larger than necessary 36 and that the intestines are too long and too permeable for modern diets. 37 In 2003, we described and published 38 the early results from a surgical proposal for treating obesity that included vertical gastric resection (in the same way as already extensively used in the "duodenal switch" technique 39 ) in association with omentectomy and midgut enterectomy in three patients. This procedure leaves three meters of small bowel, which is the lower limit for the length of the normal small bowel.…”

Section: Peptide Yy (Pyy) and Oxyntomodulinmentioning

confidence: 99%

Preliminary results from digestive adaptation: a new surgical proposal for treating obesity, based on physiology and evolution

et al. 2006

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CONTEXT AND OBJECTIVE: Most bariatric surgical techniques include essentially non-physiological features like narrowing anastomoses or bands, or digestive segment exclusion, especially the duodenum. This potentially causes symptoms or complications. The aim here was to report on the preliminary results from a new surgical technique for treating morbid obesity that takes a physiological and evolutionary approach. DESIGN AND SETTING: Case series description, in Hospital Israelita Albert Einstein and Hospital da Polícia Militar, São Paulo, and Hospital Vicentino, Ponta Grossa, Paraná. METHODS: The technique included vertical (sleeve) gastrectomy, omentectomy and enterectomy that retained three meters of small bowel (initial jejunum and most of the ileum), i.e. the lower limit for normal adults. The operations on 100 patients are described. RESULTS: The mean follow-up was nine months (range: one to 29 months). The mean reductions in body mass index were 4.3, 6.1, 8.1, 10.1 and 10.7 kg/m², respectively at 1, 2, 4, 6 and 12 months. All patients reported early satiety. There was major improvement in comorbidities, especially diabetes. Operative complications occurred in 7% of patients, all of them resolved without sequelae. There was no mortality. CONCLUSIONS: This procedure creates a proportionally reduced gastrointestinal tract, leaving its basic functions unharmed and producing adaptation of the gastric chamber size to hypercaloric diet. It removes the sources of ghrelin, plasminogen activator inhibitor-1 (PAI-1) and resistin production and leads more nutrients to the distal bowel, with desirable metabolic consequences. Patients do not need nutritional support or drug medication. The procedure is straightforward and safe.

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Section: Peptide Yy (Pyy) and Oxyntomodulinmentioning

confidence: 99%

Preliminary results from digestive adaptation: a new surgical proposal for treating obesity, based on physiology and evolution

et al. 2006

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“…We introduced thoracoscopy in 1993 and performed bilateral sympathectomies for hyperhidrosis, emphysematous bullae [23], neurilenoma [24] and the 1 st pericardial window due to effusion in the country [25]. In 2003 all thoracic surgery was transferred to the newly created regional referral center.…”

Section: Thoracic Surgerymentioning

confidence: 99%

Four Decades of Advances in General Surgery at a Spanish Community Hospital

2017

International Journal of Research Studies in Medical and Health

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“…The second benefit is that the transverse incision facilitates post-bariatric plastic surgery, as transpositions of the navel are readily performed with a single scar just above the pubis (Figure 1c). Our group later published an intermediate study on the DS [29] followed by comparative studies of VBG and DS [30]. In 1990, the ASBS started Obesity Surgery, as their official medium for reporting scholarly research and was included into the Index Medicus in 1995.…”

Section: S-beginnings Of Bs In Alcoymentioning

confidence: 99%