Ductal Adenocarcinoma of the Prostate: A Case Report

Hayashi, Yutaro; Kawahara, Takashi; Iwashita, Hiromichi; Shimokihara, Kota; Tsutsumi, Sohgo; Takamoto, Daiji; Mochizuki, Takashi; Hattori, Yusuke; Teranishi, Jun‐ichi; Miyoshi, Yasuhide; Yumura, Yasushi; Yao, Masahiro; Inayama, Yoshiaki; Uemura, Hiroji

doi:10.1159/000453448

Cited by 3 publications

(2 citation statements)

References 5 publications

(8 reference statements)

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“…Ductal PC is a rare histologic subtype, accounting for 0.4% to 0.8% of all prostate malignancies and associated with poor prognosis. [1][2][3] Most patients with ductal PC have normal PSA levels that limit biochemical disease follow-up. 4 18 F-labeled PSMA compounds have been recently introduced, promising higher diagnostic accuracy due to higher image quality and longer half-life of 18 F enabling higher clearance at later time point imaging.…”

Section: Figurementioning

confidence: 99%

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Ductal Variant of Prostate Cancer

Alabed¹

2021

Clin Nucl Med

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A 51-year-old man with high-grade ductal variant of prostate cancer with normal prostate-specific antigen (PSA) levels underwent radical prostatectomy. Follow-up 18F–prostate-specific membrane antigen-targeted ligand 1007 (PSMA-1007) PET/CT revealed enlarged PSMA-expressing left common iliac node. Patient was placed on androgen deprivation therapy and was lost to follow-up. Repeat 18F-PSMA PET/CT scan after 16 months showed disease progression. PSA levels were still within normal limits. This case highlights the utility of 18F-PSMA PET/CT for staging and follow-up of patients with this rare ductal variant prostate cancer with normal PSA levels.

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Section: Figurementioning

confidence: 99%

“…A new PSMA-expressing presacral nodal mass (arrowhead) was seen (SUV max , 4.4), in keeping with metastatic disease. Ductal PC is a rare histologic subtype, accounting for 0.4% to 0.8% of all prostate malignancies and associated with poor prognosis 1–3 . Most patients with ductal PC have normal PSA levels that limit biochemical disease follow-up 4 .…”

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confidence: 99%

Ductal Variant of Prostate Cancer

Alabed¹

2021

Clin Nucl Med

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Advanced ductal adenocarcinoma of the prostate in a 71-year old male: A case report and literature review

Yahaya

2020

Human Pathology: Case Reports

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Radiotherapy for ductal carcinoma of the prostate: an analysis based on the Japanese radiation oncology study group survey

Kawamura

Nakamura

Yoshioka

et al. 2022

Japanese Journal of Clinical Oncology

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Background The clinical characteristics of prostate ductal carcinoma is still unclear, and treatment strategy has not yet been established due to its rarity. Therefore, we conducted a multicenter survey of radiation therapy for prostate ductal carcinoma in Japan. Method Data of patients with ductal carcinoma of the prostate treated with radiation therapy between 1996 and 2018 were extracted from the database of each facility. Results Fifty-two treatment records of 41 patients were collected from nine institutions. The treatment purpose and situations were varied curative intent to palliation. Twenty-eight patients received curative treatments. The median follow-up period of these patients was 68 months. Androgen deprivation therapy was combined with radiation therapy in 26 cases (93%). X-ray and particle irradiation was used. Radiation dose range was 63–78 Gy; 5-year overall survival, progression-free survival and biochemical relapse-free survival were 87.0, 79.3 and 79.3%, respectively. One patient experienced Grade 3 radiation proctitis and one experienced Grade 3 radiation cystitis. There were no Grade 4 or worse adverse events. Conclusion Most patient received similar treatment with adenocarcinoma of prostate, and the clinical results were compatible. For more reliable evidence, further studies are required.

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Ductal Adenocarcinoma of the Prostate: A Case Report

Cited by 3 publications

References 5 publications

Ductal Variant of Prostate Cancer

Ductal Variant of Prostate Cancer

Advanced ductal adenocarcinoma of the prostate in a 71-year old male: A case report and literature review

Radiotherapy for ductal carcinoma of the prostate: an analysis based on the Japanese radiation oncology study group survey

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