Dual-targeting magnetic fluorescent mesoporous organosilicon hollow nanospheres for gambogic acid loading, sustained release and anti-tumor properties

Chang, Ziling; Yang, Yuxiang; Zhao, Bo; Li, Huafei; Guan, Yuxia; Zhao, Yi; Yuan, Hongming; Ni, Chaoying

doi:10.1016/j.molliq.2022.119412

Cited by 5 publications

(3 citation statements)

References 28 publications

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“…In vivo assessment showed that the nanocomposites could inhibit tumor proliferation and had magnetic targeting ability. 95 In a recent study, poly(L-lactide)-poly(ethylene glycol)-poly(Llactide) triblock copolymer (PLLA-PEG-PLLA)-based nanocomposites co-encapsulated with black phosphorus quantum dots (BPQDs) and GA employing the supercritical carbon dioxide approach (Fig. 19).…”

Section: Inorganic Nanocarriersmentioning

confidence: 99%

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Emerging tendencies for the nano-delivery of gambogic acid: a promising approach in oncotherapy

Fahmy,

Elghanam,

Rashid

et al. 2024

RSC Adv.

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Section: Inorganic Nanocarriersmentioning

confidence: 99%

“…In vivo assessment showed that the nanocomposites could inhibit tumor proliferation and had magnetic targeting ability. 95 …”

Section: Gambogic Acid Nano-delivery Using Nano-particulatesmentioning

confidence: 99%

Emerging tendencies for the nano-delivery of gambogic acid: a promising approach in oncotherapy

Fahmy,

Elghanam,

Rashid

et al. 2024

RSC Adv.

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“…Among the other morphologies, hollow nanostructures have attracted recent research interest due to their large pore volume, low mass density, and high surface-to-volume ratio compared to their solid counterparts [ 17 , 18 , 19 ]. Especially in bioapplication, the hollow void encapsulates the drug molecules and releases them when necessary [ 20 ]. The porous hollow shell is a diffusion barrier for the controlled release of payloads.…”

Section: Introductionmentioning

confidence: 99%

Single-Micelle-Templated Synthesis of Hollow Barium Carbonate Nanoparticle for Drug Delivery

et al. 2023

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A laboratory-synthesized triblock copolymer poly(ethylene oxide-b-acrylic acid-b-styrene) (PEG-PAA-PS) was used as a template to synthesize hollow BaCO3 nanoparticles (BC-NPs). The triblock copolymer was synthesized using reversible addition–fragmentation chain transfer radical polymerization. The triblock copolymer has a molecular weight of 1.88 × 104 g/mol. Transmission electron microscopy measurements confirm the formation of spherical micelles with a PEG corona, PAA shell, and PS core in an aqueous solution. Furthermore, the dynamic light scattering experiment revealed the electrostatic interaction of Ba2+ ions with an anionic poly(acrylic acid) block of the micelles. The controlled precipitation of BaCO3 around spherical polymeric micelles followed by calcination allows for the synthesis of hollow BC-NPs with cavity diameters of 15 nm and a shell thickness of 5 nm. The encapsulation and release of methotrexate from hollow BC-NPs at pH 7.4 was studied. The cell viability experiments indicate the possibility of BC-NPs maintaining biocompatibility for a prolonged time.

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Superparamagnetic iron oxide nanoparticles target BxPC-3 cells and silence MUC4 for the treatment of pancreatic cancer

Pu,

Ke,

et al. 2023

Biochimica et Biophysica Acta (BBA) - General Subjects

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Dual-targeting magnetic fluorescent mesoporous organosilicon hollow nanospheres for gambogic acid loading, sustained release and anti-tumor properties

Cited by 5 publications

References 28 publications

Emerging tendencies for the nano-delivery of gambogic acid: a promising approach in oncotherapy

Emerging tendencies for the nano-delivery of gambogic acid: a promising approach in oncotherapy

Single-Micelle-Templated Synthesis of Hollow Barium Carbonate Nanoparticle for Drug Delivery

Superparamagnetic iron oxide nanoparticles target BxPC-3 cells and silence MUC4 for the treatment of pancreatic cancer

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