Dual-stimuli-responsive porous polymer enzyme reactor for tuning enzymolysis efficiency

Reversible transformation of peptide assembly between densified-polysarcosine-driven kinetically and helix-orientation-driven thermodynamically stable morphologies

“…Indeed, this is considered a pivotal property when it comes to the drug delivery, 8,9 tissue engineering 10,11 and nanoreactor application fields. 12,13 One of the most widely used smart materials especially in the biomedical field is temperature-responsive polymers. Although the literature presents several examples for thermoresponsive polymers, new materials, especially those from natural sources, with new properties are required.…”

“…Indeed, this is considered a pivotal property when it comes to the drug delivery, 8,9 tissue engineering 10,11 and nanoreactor application fields. 12,13…”

Thermo-responsive polymer-modified metal–organic frameworks as soft–rigid enzyme-reactors for enhancement of enzymolysis efficiency using a controllable embedding protocol

“…For example, pH-sensitive, temperaturesensitive and light-sensitive polymers have been applied for enzyme immobilization and the resulting nano-reactors enhanced the enzymolysis efficiency. [31][32][33] Combining the benefits of both soft stimuli-responsive polymers and the rigid frameworks of MOFs to form ''stimuli-responsive polymer-MOFs'' may provide an opportunity to greatly enhance their performance. Recently, the concept of polymer-MOFs complexes has received wide attention.…”