Dual-stimuli responsive nanoparticles (UCNP-CD@APP) assembled by host-guest interaction for drug delivery

Hao, Weiju; Liu, Danyang; Wang, Yizhou; Han, Xia; Xu, Shouhong; Liu, Honglai

doi:10.1016/j.colsurfa.2017.10.038

Cited by 22 publications

(21 citation statements)

References 28 publications

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“…This copolymer was inserted into the host β-cyclodextrins. The azo group has a cis-trans reversibly isomerism, that are transformed into one another by near-infrared light (NIR, 980 nm) and caused the reversible insertion into the cyclodextrin ring [44]. Table 1.…”

Section: Responsive Cyclodextrinsmentioning

confidence: 99%

Cyclodextrins in Drug Delivery Systems and Their Effects on Biological Barriers

et al. 2019

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Cyclodextrins are widely used excipients, composed of glucopyranose units with a cyclic structure. One of their most important properties, is that their inner cavity is hydrophobic, while their surface is hydrophilic. This enables them for the complex formation with lipophilic molecules. They have several applications in the pharmaceutical field like solubility enhancers or the building blocks of larger drug delivery systems. On the other hand, they have numerous effects on cells or biological barriers. In this review the most important properties of cyclodextrins and cyclodextrin-based drug delivery systems are summarized with special focus on their biological activity.

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Section: Responsive Cyclodextrinsmentioning

confidence: 99%

Cyclodextrins in Drug Delivery Systems and Their Effects on Biological Barriers

et al. 2019

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“…pH sensitivity basically triggered the DOX release and clearer cytotoxic effect of the system on HeLa cells than free DOX are further investigated using their photo responsive property. 204 Dual response of temperature and H2O2 in cyclodextrin based system was reported by Guo and his co workers.…”

Section: Multistimuli Responsivenessmentioning

confidence: 88%

Recent Development of Polysaccharide-Derived Hydrogel: Properties, Stimuli-Responsiveness and Bioapplications

Mukherjee

2022

Preprint

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Hydrogels are three-dimensional, hydrophilic, polymeric frameworks, constructed through diverse physical or chemical crosslinks. Recent research focuses on their physiological stimuli sensitivity enhancing bioapplications. Biopolymers with responsiveness to local environment like temperature, pH etc. form the foundation in this regard, around which all major natural processes are circulated. Polysaccharides, being most the abundant biopolymers and essential constituent of our daily food like cereals and fruits, are readily available in nature. Hence, among numerous biomacromolecules, polysaccharides are extensively used to prepare hydrogel recently. However, incorporation of certain properties to these gels through derivatization can trigger stimuli responsiveness suitable for various applications especially in biomedical field inspired from the mother nature. For example, in situ cross-linking ability may deliver an intermediate platform between solid scaffolds and saline injections through reversible or irreversible sol-gel transition. Easy injectability provides patient’s relief through reducing recovery time and inflectional hazards. Self recovery of gel within body results automatic inflammation and damage recovery of tissues. This review provides a detail impression on the synthesis of natural polysaccharide derived hydrogel network with structural classification to bulk, supramolecular, micro and nano gel. Several properties important from biomedical point such as in situ, injectable, self healing nature of these hydrogels and various physical, chemical, or biochemical stimuli-responsive characteristics are discussed further. Lastly, their major bioapplications are highlighted.

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“…Weiju Hao and co-workers promisingly studied about dual stimuli responsive NPs for enhanced drug delivery [22]. Dual stimuli responsive NPs with pH-and photo-responsibility were synthesized via host-guest reaction.…”

Section: Multiple Stimuli Responsive CD Based Materialsmentioning

confidence: 99%

Multiple stimuli responsive cyclodextrin based smart materials for drug delivery: a review

et al. 2021

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In this review we discuss about the research advances in multiple stimuli responsive cyclodextrin (CD) based smart materials. CD based systems which are responsive to temperature, pH, enzymes, light, redox etc. along with various applications of these systems in the biomedical area are extensively covered. Current challenges and future perspectives of these smart stimuli-responsive drug delivery systems are also discussed.

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Dual-stimuli responsive nanoparticles (UCNP-CD@APP) assembled by host-guest interaction for drug delivery

Cited by 22 publications

References 28 publications

Cyclodextrins in Drug Delivery Systems and Their Effects on Biological Barriers

Cyclodextrins in Drug Delivery Systems and Their Effects on Biological Barriers

Recent Development of Polysaccharide-Derived Hydrogel: Properties, Stimuli-Responsiveness and Bioapplications

Multiple stimuli responsive cyclodextrin based smart materials for drug delivery: a review

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