“…Since stevioside tastes about 300 times sweeter than sucrose in a 0.4 g/100 mL solution (Geuns, 2003), this compound is considered as a promising sugar substitute and low-caloric sweetener, and has been used in variety of foods, such as soft drinks, fruits, chocolates, soy sauce, chewing gum, yogurt, and other products (Garcia-Noguera, Weller, Oliveira, Rodrigues, & Fernandes, 2010;Kroyer, 2010;Shah, Jones, & Vasiljevic, 2010). A number of studies have suggested that stevioside may also exert therapeutic benefits, for its anti-hyperglycaemic (Gregersen, Jeppesen, Holst, & Hermansen, 2004), anti-hypertensive (Chan et al, 2000), anti-inflammatory (Boonkaewwan, Toskulkao, & Vongsakul, 2006), anti-tumour (Yasukawa, Kitanaka, & Seo, 2002), anti-diarrhoeal (Pariwat, Homvisasevongsa, Muanprasat, & Chatsudthipong, 2008), and immunomodulatory properties (Sehar, Kaul, Bani, Pal, & Saxena, 2008).…”