Dual Source Computed Tomography in Patients with Congenital Heart Disease

Ihlenburg, S; Rompel, Oliver; Rueffer, André; Purbojo, Ariawan; Cesnjevar, Robert; Dittrich, Sven; Gloeckler, Martin

doi:10.1055/s-0033-1349791

Cited by 8 publications

(4 citation statements)

References 16 publications

(26 reference statements)

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“…Compared with traditional CT, the scanning speed is faster and the time resolution is higher. Isotropic volume data and higher spatial resolution make three‐dimensional reconstruction images more perfect recently . It can clearly show the normal and pathological complex anatomy of the cardiovascular system, and gradually becomes an important diagnostic method for congenital heart disease.…”

Section: Introductionmentioning

confidence: 99%

“…Isotropic volume data and higher spatial resolution make three-dimensional reconstruction images more perfect recently. 8,9 It can clearly show the normal and pathological complex anatomy of the cardiovascular system, and gradually becomes an important diagnostic method for congenital heart disease. For postoperative congenital heart disease, 64-CT angiography can be used to observe the anastomosis after surgery, the position and patency of the artificial blood vessel, and the peripheral pulmonary artery after the intervertebral patch.…”

Section: Introductionmentioning

confidence: 99%

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Comparison of echocardiography and 64‐slice spiral computed tomography in the diagnosis of congenital heart disease in children

Mei

Nie

Yang

et al. 2018

J of Cellular Biochemistry

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The diagnosis of congenital heart disease in children has been an issue in the medical community. Timely diagnosis and treatment can provide a greater guarantee for children's healthy growth. In recent years, there have been more and more studies on the diagnosis of congenital heart disease in children. This paper compares the advantages and disadvantages of echocardiography and 64-slice spiral computed tomography (CT) in the diagnosis of congenital heart disease in children. In clinical trials, we also tested 64 patients with spiral computed tomography (SCT) and transthoracic echocardiography (TTE) detection of patients and then confirmed the accuracy of the diagnosis by the surgical methods. The two methods of detection, the rate of missed diagnosis, and the rate of misdiagnosis were counted. Through the test results and pathological diagnosis results, the diagnostic accuracy of the two methods were all above 90%, each with its own advantages and disadvantages. The sensitivity of echocardiographic in detecting intracardiac structure abnormalities was relatively high, but when the diagnosis of extracardiac structural abnormalities less than 64-slice spiral CT method, misdiagnosis of TTE was mainly due to extracardiac vascular malformations. Therefore, it is recommended to combine the two methods to improve the diagnosis of congenital heart disease in children.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Comparison of echocardiography and 64‐slice spiral computed tomography in the diagnosis of congenital heart disease in children

Mei

Nie

Yang

et al. 2018

J of Cellular Biochemistry

View full text Add to dashboard Cite

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“…First, this might be explained by the low incidence of coronary stenosis in children or adolescents, and the cautious application of CT in children with CAD. Second, radiation burden has always been a concern in pediatric radiology, and the use of 64-slice CT for pericardial narrowing in children is unlikely due to the higher radiation burden of the 64-slice CT versus 256-slice CT and dual source CT, 20 which limited the application of 64- slice CT in the diagnosis of coronary stenosis in children. Third, only those with ≥50% obstructive lesions in coronary arteries were included in the analysis.…”

Section: Discussionmentioning

confidence: 99%

Diagnostic accuracy of coronary angiography using 64-slice computed tomography in coronary artery disease

Yang

Guo

Sheng

et al. 2015

SMJ

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Objectives:To conduct a meta-analysis and investigate the diagnostic value of 64-slice computed tomography (CT) angiography for diagnosing coronary artery disease (CAD) in patients.Methods:A comprehensive literature search from March 2005 to August 2014 was performed on the following databases: Cochrane Library; Medline; EmBase; PubMed; and BioMed Central database. As a reference standard, studies that assessed 64-slice CT angiography in detecting coronary artery stenosis (CAS) with invasive coronary angiography were included. Coronary artery stenosis was defined as ≥50% diameter stenosis. Diagnostic value was determined by pooling sensitivity, specificity, positive likelihood ratio (PLR) and negative likelihood ratio (NLR) values at segment-level analysis. Diagnostic accuracy was undertaken using area under the curve (AUC) value and summary receiver operating characteristic (SROC) curves. Publication bias was examined by Deek’s funnel plot asymmetry test.Results:Eight studies were included in the analysis, enrolling a total of 579 patients (7,407 segment coronary vessels). At segment-level, pooled sensitivity value was 90% (95% confidence interval [CI]: 83-95%), specificity was 91% (95% CI: 61-98%), PLR value was 9.7 (95% CI: 1.8-53.3), and NLR value was 0.11 (95% CI: 0.05-0.22) for CAS. Optimal cut-off point of sensitivity was 90%, and specificity under the SROC curve was 91%. The AUC value was 0.94.Conclusion:The 64-slice CT angiography is a reliable tool for detection of CAD when using a cut-off of ≥50% diameter stenosis in elderly population.

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“…With high temporal and spatial resolutions, DSCT can comprehensively evaluate anatomical characteristics. DSCT can be currently utilized to obtain images with good quality at a lower radiation dose, without considering the effects of heart rate for pediatric patients [ 7 , 8 ]. DSCT is now recognized as a routine examination method for various kinds of CHD, especially complex CHD [ 9 , 10 , 11 ].…”

Section: Introductionmentioning

confidence: 99%

Assessment of transposition of the great arteries associated with multiple malformations using dual-source computed tomography

et al. 2017

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PurposeTo determine the value of dual-source computed tomography (DSCT) in depicting the morphological characteristics and diagnosing the associated malformations for patients with transposition of the great arteries (TGA) before surgery.Materials and methodsTwenty-five patients with TGA who underwent DSCT and transthoracic echocardiography (TTE) examination were retrospectively reviewed. The morphological types of TGA, the spatial relationship between the pulmonary artery and the aorta, as well as coronary artery-associated abnormalities were assessed by DSCT. In contrast to TTE, the diagnostic accuracy of associated malformations on DSCT were analyzed and calculated with reference to surgical or digital subtraction angiography (DSA) findings. Effective doses (EDs) were also calculated.ResultsAmong the 25 patients, 12 (48%) had ventricular septal defects and left ventricular outflow tract stenosis. Sixteen patients (16/25, 64%) had great arteries with an oblique spatial relationship on DSCT. In addition, we found seven patients (7/25, 28%) with coronary artery malformation, including five with an abnormal coronary origin and two with signs of a myocardial bridge. According to DSA or surgical findings, DSCT was superior to TTE in demonstrating extracardiac anomalies (sensitivity, anomalies of great vessels: 100% vs. 93.33%, other anomalies: 100% vs. 46.15%). The mean estimated ED for those aged <10 years was <2 mSv (1.59 ± 0.95 mSv).ConclusionsDSCT can achieve an overall assessment of patients with TGA, including any associated malformations as well as the identification of the spatial relationship of the great arteries. DSCT can therefore be considered as an alternative imaging modality for surgical decision making.

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Dual Source Computed Tomography in Patients with Congenital Heart Disease

Cited by 8 publications

References 16 publications

Comparison of echocardiography and 64‐slice spiral computed tomography in the diagnosis of congenital heart disease in children

Comparison of echocardiography and 64‐slice spiral computed tomography in the diagnosis of congenital heart disease in children

Diagnostic accuracy of coronary angiography using 64-slice computed tomography in coronary artery disease

Assessment of transposition of the great arteries associated with multiple malformations using dual-source computed tomography

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