Dual-Responsive Nanotubes Assembled by Amphiphilic Dendrimers: Controlled Release and Crosslinking

Abstract

Although stimuli-responsive release systems have attracted great attention in medical applications, there has been no attempt at “precise” deep profile control based on such systems, which is greatly need to improve oil recovery. With this in mind, we provided a facile and simple strategy to prepare stimuli-responsive composite capsules of amphiphilic dendrimers–poly(styrene sulfonic acid) sodium/halloysite nanotubes (HNTs) via layer-by-layer (LbL) self-assembly technique, controlling the release crosslinking agent methenamine under different pH or salinity conditions. The release time of methenamine encapsulated in multilayer shells is about 40 h, which can be prolonged with the introduction of salt or shortened via the addition of acid, which accordingly induces the gelation of polyacrylamide (PAM) solutions, taking from a few hours to a dozen days. This study provided a novel approach for controllable release of chemical agents and controllable crosslinking of deep profiles in many application fields.

Uncertainty quantification for predictions of atomistic neural networks

“…For chemical applications, ensemble methods which involve the training and evaluation of several independently trained statistical models to obtain the quantities of interest (average and variance for an observation) have been used. 36,37 Despite their widespread use their disadvantage is the high computational cost they incur. An alternative to this are methods based on Gaussian process regression 38,39 .…”