Dual‐Responsive Material Based on Catechol‐Modified Self‐Immolative Poly(Disulfide) Backbones

Abstract

Functional materials engineered to degrade upon triggering are in high demand due their potentially lower impact on the environment as well as their use in sensing and in medical applications.H ere,s timuli-responsive polymers are prepared by decorating as elf-immolative poly(dithiothreitol) backbone with pendant catechol units.T he highly functional polymer is fashioned into stimuli-responsive gels,f ormed through pH-dependent catecholato-metal ion cross-links.T he gels degrade in response to specific environmental changes, either by addressing the pH responsive,non-covalent, catecholato-metal complexes,o rb ya ddition of at hiol. The latter stimulus triggers end-to-end depolymerization of the entire self-immolative backbone through end-cap replacement via thiol-disufide exchanges.G el degradation is visualizedb y release of ad ye from the supramolecular gel as it itself is converted into smaller molecules.

Marine Biodegradation of Poly(butylene succinate) Incorporating Disulfide Bonds Triggered by a Switch Function in Response to Reductive Stimuli

“…On the other hand, disulfide bonds are reduction-responsive and undergo reductive cleavage under low ORP conditions to form two thiol groups. Polymers with disulfide bonds in the main chain degrade to low-molar-mass compounds in response to a change in ORP , and are used in protein conjugation, , drug delivery systems, , degradable polymers, , and polymer recycling to monomers. , Disulfide bonds in polymers can function as a switch for the initiation of biodegradation. We previously reported the reductive stimuli biodegradation control of poly­(butylene dithiodiglycolate) (PBDTG) comprising 1,4-butanediol (BD) and dithioglycolic acid (DTG).…”

Chemically recyclable polymer materials: polymerization and depolymerization cycles

“…229 Over the past decade, researchers have been exploring various types of SIP, including (thio)carbamates, (thio)carbonates, phthalaldehydes, benzyl ethers/esters, glyoxylates, etc., which have been summarized in many review articles. [230][231][232][233][234][235][236] Therefore, this review will not go into details, but only illustrates one example of the poly(o-phthalaldehyde) (PPA) polymer that can be depolymerized into the starting o-PA monomer. As shown in the literature, the ceiling temperature (T c ) of PPA is about −40 °C.…”

Comparison of the properties of silica aerogel doped with two different laser dyes: Crystal violet and Rhodamine B

“…The behavior of dye in non-polar solutions suggests that the solvent interaction around the dye cation is lessening as the solvent molecules self-associate (Shen et al, 2021). In addition to dyes made as catalysis for modifying the converted gel through adding enhancements to the characterization of the surface silica compared with the non-doped product (Agergaard, Sommerfeldt, Pedersen, Birkedal, & Daasbjerg, 2021). As a result, the surface area, pour volume, and average pour diameter are reduced.…”