Dual-responsive carbon dots-based luminophore for ratiometric fluorescence and room-temperature phosphorescence detection of oxytetracycline

Wang, Qin; Tan, Qiuxia; Zhao, Shaojing; Zhang, Kui; Chen, Jianmin; Lan, Minhuan

doi:10.1016/j.cej.2023.144061

Cited by 4 publications

(3 citation statements)

References 44 publications

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“…The detection limits were calculated as 3.2 nM for fluorescence and 0.27 𝜇M for phosphorescence. [66] ALP (alkaline phosphatase) can catalyze the hydrolysis of sodium p-nitrophenyl phosphate (PNP) to generate p-nitrophenol. [67] Liu et al employed the inner Reproduced with permission.…”

Section: Data Encryptionmentioning

confidence: 99%

Endowing Carbon Dots with Long‐Lived Phosphorescence Emission in Aqueous Solutions

Li,

Zhao,

Zhang

et al. 2023

Adv Funct Materials

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Room temperature phosphorescent carbon dots (RTP CDs) have received increasing attention in recent years due to their outstanding optical properties and potential applications. It is worth noting that RTP CDs in aqueous solution have inspired special interests because of their low toxicity, long lifetime, and ability to avoid autofluorescence and background fluorescence, exhibiting wide application prospects in time‐resolved biological imaging and sensing. However, achieving phosphorescent CDs in aqueous solutions remains a considerable challenge because water molecules and oxygen can cause the deactivation of triplet‐state excitons, resulting in phosphorescence quenching. Several strategies have been proposed to counter the problem including encapsulated CDs in a rigid matrix, hydrogen bonding, and covalent bonding fixation. Consequently, a more significant number of RTP CDs materials with excellent optical stability, long lifetime, and multicolor are successfully obtained. Herein, the recent development of RTP CDs materials in aqueous solution as well as the corresponding fabricated strategies and luminescence mechanism is detailly summarized and reviewed. Furthermore, various applications of water‐phase RTP CDs materials in information security, sensing, bioimaging, light‐emitting diodes, and fingerprinting are also discussed. Finally, an outlook on the development of CDs materials and applications is proposed.

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Section: Data Encryptionmentioning

confidence: 99%

Endowing Carbon Dots with Long‐Lived Phosphorescence Emission in Aqueous Solutions

Li,

Zhao,

Zhang

et al. 2023

Adv Funct Materials

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“…Nanomaterials with enzyme-mimicking catalytic activity (i.e., nanozymes) have drawn considerable attention during the past several years since the pioneering report by Yang et al A series of nanozymes with excellent enzyme-mimicking performance and accurate controllability were developed, which have been widely applied in biological imaging, − environmental monitoring, − enzyme-like catalysis, , and antineoplastic. , Among all of the nanozymes identified, noble-metal-based nanomaterials are among the most popular ones to be employed for environmental monitoring with nanomolar-level detection limits by virtue of their high catalytic activity and signal amplification. , However, single-noble-metal-based nanomaterials are often highly toxic and easily aggregated, which will result in their biological incompatibility and catalytic instability. What’s more, as far as we know, there have been few reports on absolute noble metal quantum dot nanozymes with dual colorimetric and fluorescent sensing applications − so far.…”

Section: Introductionmentioning

confidence: 99%

Biocompatible Folic-Acid-Strengthened Ag–Ir Quantum Dot Nanozyme for Cell and Plant Root Imaging of Cysteine/Stress and Multichannel Monitoring of Hg²⁺ and Dopamine

Yan,

Tang,

Zhang

et al. 2024

Anal. Chem.

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To boost the enzyme-like activity, biological compatibility, and antiaggregation effect of noble-metal-based nanozymes, folic-acid-strengthened Ag−Ir quantum dots (FA@ Ag−Ir QDs) were developed. Not only did FA@Ag−Ir QDs exhibit excellent synergistic-enhancement peroxidase-like activity, high stability, and low toxicity, but they could also promote the lateral root propagation of Arabidopsis thaliana. Especially, ultratrace cysteine or Hg 2+ could exclusively strengthen or deteriorate the inherent fluorescence property with an obvious "turn-on" or "turn-off" effect, and dopamine could alter the peroxidase-like activity with a clear hypochromic effect from blue to colorless. Under optimized conditions, FA@Ag−Ir QDs were successfully applied for the turn-on fluorescence imaging of cysteine or the stress response in cells and plant roots, the turn-off fluorescence monitoring of toxic Hg 2+ , or the visual detection of dopamine in aqueous, beverage, serum, or medical samples with low detection limits and satisfactory recoveries. The selective recognition mechanisms for FA@Ag−Ir QDs toward cysteine, Hg 2+ , and dopamine were illustrated. This work will offer insights into constructing some efficient nanozyme sensors for multichannel environmental analyses, especially for the prediagnosis of cysteinerelated diseases or stress responses in organisms.

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“…So far, various technologies, including chromatography, mass spectrometry, electrochemistry, and spectroscopy, have been developed to measure DOX . It is worth noting that, compared to other technologies, fluorescence and colorimetry methods have gained attention in detecting DOX due to their simplicity, high sensitivity, convenience, and visibility. − …”

Section: Introductionmentioning

confidence: 99%

Bismuth, Nitrogen-Codoped Carbon Dots as a Dual-Read Optical Sensing Platform for Highly Sensitive, Ultrarapid, Ratiometric Detection of Doxorubicin

Du,

Gao,

Zhang

et al. 2023

ACS Omega

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Doxorubicin (DOX) is a potent anticancer drug, but it has side effects on normal tissues, particularly myocardial cells. Therefore, it is crucial to detect the DOX concentration in body fluids for effective clinical treatment. In this work, N,Bi-codoped CDs (Bi,N-CDs) were synthesized through a one-step hydrothermal method to carbonize the raw materials of 2,4-dinitroaniline and bismuth nitrate. The resulting Bi,N-CDs showed a reduced emission at 490 nm and an enhanced emission at 590 nm in the presence of DOX. The ratio of fluorescence (FL) intensity (F 590 /F 490 ) was found to be a reliable indicator of DOX concentration, ranging from 0.05 to 30 μM and 40−200 μM, with detection limits (LOD) of 34 and 24 nM, respectively. A ratiometric fluorescence nanoprobe was established for highly selective and sensitive detection of DOX using a specific electrostatic interaction and inner filter effect between Bi,N-CDs and DOX. Meanwhile, Bi,N-CDs exhibited a distinct color change ranging from yellow to orange-red when exposed to DOX, allowing for a colorimetric method to measure DOX levels in the range of 0.05−30 μM, with a detection limit of 169 nM. The probe was triumphantly used to monitor DOX in actual samples via a dual-mode optical sensing strategy. This study contributes to the development of heteroatom-doped CDs and expands their potential applications for detecting biological samples.

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Dual-responsive carbon dots-based luminophore for ratiometric fluorescence and room-temperature phosphorescence detection of oxytetracycline

Cited by 4 publications

References 44 publications

Endowing Carbon Dots with Long‐Lived Phosphorescence Emission in Aqueous Solutions

Endowing Carbon Dots with Long‐Lived Phosphorescence Emission in Aqueous Solutions

Biocompatible Folic-Acid-Strengthened Ag–Ir Quantum Dot Nanozyme for Cell and Plant Root Imaging of Cysteine/Stress and Multichannel Monitoring of Hg²⁺ and Dopamine

Bismuth, Nitrogen-Codoped Carbon Dots as a Dual-Read Optical Sensing Platform for Highly Sensitive, Ultrarapid, Ratiometric Detection of Doxorubicin

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Dual-responsive carbon dots-based luminophore for ratiometric fluorescence and room-temperature phosphorescence detection of oxytetracycline

Cited by 4 publications

References 44 publications

Endowing Carbon Dots with Long‐Lived Phosphorescence Emission in Aqueous Solutions

Endowing Carbon Dots with Long‐Lived Phosphorescence Emission in Aqueous Solutions

Biocompatible Folic-Acid-Strengthened Ag–Ir Quantum Dot Nanozyme for Cell and Plant Root Imaging of Cysteine/Stress and Multichannel Monitoring of Hg2+ and Dopamine

Bismuth, Nitrogen-Codoped Carbon Dots as a Dual-Read Optical Sensing Platform for Highly Sensitive, Ultrarapid, Ratiometric Detection of Doxorubicin

Contact Info

Product

Resources

About

Biocompatible Folic-Acid-Strengthened Ag–Ir Quantum Dot Nanozyme for Cell and Plant Root Imaging of Cysteine/Stress and Multichannel Monitoring of Hg²⁺ and Dopamine