Dual production of polyhydroxyalkanoates and antibacterial/antiviral gold nanoparticles

Paxinou, Alexandra; Marcello, Elena; Vecchiato, Vittoria; Erman, Lara; Wright, Edward; Noble, Brendon; McCormick, Adele; Basnett, Pooja

doi:10.3389/fnano.2023.1243056

Front. Nanotechnol.

2023

DOI: 10.3389/fnano.2023.1243056

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Dual production of polyhydroxyalkanoates and antibacterial/antiviral gold nanoparticles

Alexandra Paxinou,

Elena Marcello,

Vittoria Vecchiato

et al.

Abstract: Gold nanoparticles (AuNPs) have been explored for their use in medicine. Here, we report a sustainable, and cost-effective method to produce AuNPs using a bacterial strain such as Pseudomonas mendocina CH50 which is also known to be a polyhydroxyalkanoate (PHA) producer. A cell-free bacterial supernatant, which is typically discarded after PHA extraction, was used to produce spherical AuNPs of 3.5 ± 1.5 nm in size as determined by Transmission Electron Microscopy (TEM) analysis. The AuNPs/PHA composite coating… Show more

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2024

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Cited by 2 publications

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A review on microbes mediated resource recovery and bioplastic (polyhydroxyalkanoates) production from wastewater

Ahuja,

Singh,

Mahata

et al. 2024

Microb Cell Fact

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Background Plastic is widely utilized in packaging, frameworks, and as coverings material. Its overconsumption and slow degradation, pose threats to ecosystems due to its toxic effects. While polyhydroxyalkanoates (PHA) offer a sustainable alternative to petroleum-based plastics, their production costs present significant obstacles to global adoption. On the other side, a multitude of household and industrial activities generate substantial volumes of wastewater containing both organic and inorganic contaminants. This not only poses a threat to ecosystems but also presents opportunities to get benefits from the circular economy. Main body of abstract Production of bioplastics may be improved by using the nutrients and minerals in wastewater as a feedstock for microbial fermentation. Strategies like feast-famine culture, mixed-consortia culture, and integrated processes have been developed for PHA production from highly polluted wastewater with high organic loads. Various process parameters like organic loading rate, organic content (volatile fatty acids), dissolved oxygen, operating pH, and temperature also have critical roles in PHA accumulation in microbial biomass. Research advances are also going on in downstream and recovery of PHA utilizing a combination of physical and chemical (halogenated solvents, surfactants, green solvents) methods. This review highlights recent developments in upcycling wastewater resources into PHA, encompassing various production strategies, downstream processing methodologies, and techno-economic analyses. Short conclusion Organic carbon and nitrogen present in wastewater offer a promising, cost-effective source for producing bioplastic. Previous attempts have focused on enhancing productivity through optimizing culture systems and growth conditions. However, despite technological progress, significant challenges persist, such as low productivity, intricate downstream processing, scalability issues, and the properties of resulting PHA. Graphical abstract

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A review on microbes mediated resource recovery and bioplastic (polyhydroxyalkanoates) production from wastewater

Ahuja,

Singh,

Mahata

et al. 2024

Microb Cell Fact

View full text Add to dashboard Cite

show abstract

Valorization of Algal Biomass to Produce Microbial Polyhydroxyalkanoates: Recent Updates, Challenges, and Perspectives

Narayanasamy,

Patel,

Singh

et al. 2024

Polymers

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Biopolymers are highly desirable alternatives to petrochemical-based plastics owing to their biodegradable nature. The production of bioplastics, such as polyhydroxyalkanoates (PHAs), has been widely reported using various bacterial cultures with substrates ranging from pure to biowaste-derived sugars. However, large-scale production and economic feasibility are major limiting factors. Now, using algal biomass for PHA production offers a potential solution to these challenges with a significant environmental benefit. Algae, with their unique ability to utilize carbon dioxide as a greenhouse gas (GHG) and wastewater as feed for growth, can produce value-added products in the process and, thereby, play a crucial role in promoting environmental sustainability. The sugar recovery efficiency from algal biomass is highly variable depending on pretreatment procedures due to inherent compositional variability among their cell walls. Additionally, the yields, composition, and properties of synthesized PHA vary significantly among various microbial PHA producers from algal-derived sugars. Therefore, the microalgal biomass pretreatments and synthesis of PHA copolymers still require considerable investigation to develop an efficient commercial-scale process. This review provides an overview of the microbial potential for PHA production from algal biomass and discusses strategies to enhance PHA production and its properties, focusing on managing GHGs and promoting a sustainable future.

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Dual production of polyhydroxyalkanoates and antibacterial/antiviral gold nanoparticles

Cited by 2 publications

References 90 publications

A review on microbes mediated resource recovery and bioplastic (polyhydroxyalkanoates) production from wastewater

A review on microbes mediated resource recovery and bioplastic (polyhydroxyalkanoates) production from wastewater

Valorization of Algal Biomass to Produce Microbial Polyhydroxyalkanoates: Recent Updates, Challenges, and Perspectives

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