Dual-phase helical CT of the liver: value of an early-phase acquisition in the differential diagnosis of noncystic focal lesions.

Hoe, Lieven Van; Baert, A. L.; Gryspeerdt, Stefaan; Vandenbosh, G; Nevens, Frederik; Steenbergen, Werner Van; Marchal, Guy

doi:10.2214/ajr.168.5.9129409

Cited by 80 publications

(44 citation statements)

References 14 publications

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“…This enhancement pattern can vary from generally homogeneous enhancement in welldifferentiated HCC to irregular patchy or nodular enhancement or even entirely heterogeneous appearances in poorly differentiated lesions. Similar findings were also observed in contrast-enhanced CT studies of HCC (17,18,20).…”

Section: Discussionsupporting

confidence: 85%

Characterization of Liver Lesions with Mangafodipir Trisodium–enhanced MR Imaging: Multicenter Study Comparing MR and Dual-Phase Spiral CT

Oudkerk¹,

Torres²,

Song³

et al. 2002

Radiology

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Section: Discussionsupporting

confidence: 85%

Characterization of Liver Lesions with Mangafodipir Trisodium–enhanced MR Imaging: Multicenter Study Comparing MR and Dual-Phase Spiral CT

Oudkerk¹,

Torres²,

Song³

et al. 2002

Radiology

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“…Diagnosis was biopsy proved in one case; in the other 6 patients it was based on typical imaging findings at colour Doppler US and spiral CT [1,19,20,22,24].…”

Section: Patientsmentioning

confidence: 98%

“…In clinical practice undetermined liver lesions are often characterized with spiral CT based on characteristic enhancement pattern [18,19,20,21,22,23,24,25].…”

mentioning

confidence: 99%

Characterization of unifocal liver lesions with pulse inversion harmonic imaging after Levovist injection: preliminary results

et al. 2000

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The aim of this study was to evaluate capabilities of pulse inversion harmonic imaging (PIHI) in characterization of unifocal liver lesions. We evaluated with PIHI (HDI5000, ATL, Bothell, Wash.) and spiral CT 46 consecutive patients with a single liver lesion identified by fundamental US [7 hepatocellular carcinomas (HCC), 2 cholangiocarcinomas, 7 focal nodular hyperplasias (FNH), 17 hemangiomas and 13 metastases]. The PIHI was performed before and 30 s, 2 and 4 min after bolus administration of Levovist (2.5 g, 300 mg/ml). Scans were digitally stored and reviewed using a dedicated software. Hepatocellular carcinoma was hyperechoic on 30-s scan, and hypoechoic (n = 5) or isoechoic (n = 2) on 2-min scan. Cholangiocarcinoma had inhomogeneous persistent enhancement. Focal nodular hyperplasia was hyperechoic (n = 5) or isoechoic (n = 2) on 30-s scan, hyperechoic (n = 4), isoechoic (n = 2) or slightly hypoechoic (n = 1) on 2-min scan. Large hemangioma revealed peripheral enhancement on 30-s scan which extended centripetally on 2-min scan. Small hemangioma appeared isoechoic on 2-min scan in all but two cases in which they were hypoechoic on 2-min scans and hyperechoic on 4-min scan. Metastasis was hypoechoic on all scans, 70% with rim enhancement. Similar changes in enhancement pattern have been observed at spiral CT. The 30-s and the 2-min scans revealed a conclusive importance in characterization of HCC, cholangiocarcinoma, and large hemangioma. The 2-min scan often furnished enough information for characterization of small hemangioma and metastasis. The 4-min scan allowed characterization of two hemangiomas which appeared hypoechoic on 2-min scans. In the other cases it did not provide further information. Diagnosis of FNH is usually reached with Colour Doppler US; PIHI should be used when colour Doppler is biased by artefacts or when colour Doppler findings are not characteristic. Our results seem to show that PIHI could be a valuable alternative diagnostic approach to spiral CT for unifocal liver lesion characterization. This hypothesis needs to be confirmed with an increased number of lesions.

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“…This is what was applied in our patients. Studies suggested that when CT is used to characterize a liver lesion detected with US, the CT examination should include arterial phase and portal venous phase imaging as many incidentally discovered liver lesions are hypervascular and therefore may be demonstrated and/or characterized accurately only if arterial phase imaging is included [50,51] When the ultrasound results were correlated with the CT scanning results it showed a significant relationship at p≤0.017.That means ultrasonography is acknowledged in detection and characterization of liver lesions. Because ultrasonography has excellent spatial and contrast resolution it may therefore provide useful information regarding the liver and liver masses without the use of contrast agents as CT scans.…”

Section: Discussionmentioning

confidence: 99%

Diagnostic Performance of Imaging in Detection and Characterization of Liver Lesions

Osman¹,

Ayad²

2017

IOSR JDMS

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Dual-phase helical CT of the liver: value of an early-phase acquisition in the differential diagnosis of noncystic focal lesions.

Cited by 80 publications

References 14 publications

Characterization of Liver Lesions with Mangafodipir Trisodium–enhanced MR Imaging: Multicenter Study Comparing MR and Dual-Phase Spiral CT

Characterization of Liver Lesions with Mangafodipir Trisodium–enhanced MR Imaging: Multicenter Study Comparing MR and Dual-Phase Spiral CT

Characterization of unifocal liver lesions with pulse inversion harmonic imaging after Levovist injection: preliminary results

Diagnostic Performance of Imaging in Detection and Characterization of Liver Lesions

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