“…In 100% EtOH at 25.0 °C, the rates of solvolysis for substrates 1-8 are 3.15 ± 0.04 × 10 -5 s -1 [27], 260 ± 3 × 10 -5 s -1 [25], 1.00 ± 0.02 × 10 -5 s -1 [27], 6.73 ± 0.15 × 10 -5 s -1 [28], 1740 × 10 -5 s -1 (estimated from specific rates at lower temperature) [49], 1.51 ± 0.17 × 10 -5 s -1 , 15.9 ± 1.0 × 10 -5 s -1 , and 11.9 ± 1.1 × 10 -5 s -1 [40], respectively. For compounds 1-5 and 8 , a tetrahedral A-E transition state is proposed for their ethanolyses [25,27,28,40,49].…”