Dual-ligand 3D lammelar chiral metal–organic framework for capillary electrochromatographic enantioseparations

Synthesis Strategies, Preparation Methods, and Applications of Chiral Metal‐Organic Frameworks

“…In addition, the modified columns show excellent stability and reproducibility. Du et al [80] . synthesized a two‐ligand metal‐organic skeleton based on tryptophan and camphoric acid, which was used as a stationary phase for capillary electrochromatography when the ratio of tryptophan and camphoric acid was 1 : 1, and several common enantiomers were separated with good results.…”

Highly stable chiral Cr(iii)-based metal–organic frameworks for enantioadsorption separation of aromatic alcohols

“…Homochiral metal-organic frameworks (HMOFs), as an emerging class of chiral crystalline porous materials, have gained widespread attention for their intriguing applications in asymmetric catalysis, [1][2][3] enantioseparation, [4][5][6][7][8] chiral recognition [9][10][11][12] and other areas of asymmetry. Nevertheless, despite the appealing characteristics of HMOFs, such as their controlled synthesis, extraordinary porosity and highly accessible chiral functional sites, the limited chemical stability of most reported highly porous HMOFs has immensely hindered their industrial implementation.…”

Preparation of chiral metal–organic framework l-his-MIL-53-NH2@SiO2 composite by in situ growth and chiral post-modification strategies for HPLC enantiomeric separation

“…17 Many reports have shown the potential of CMOFs as novel CSPs for enantiomeric separation. 18–21 Also, these studies showed that the pore structure, chiral sites, morphological features and particle size of CMOFs are the key factors affecting their enantiomeric separation performance. 22 Therefore, not only the skeleton structure of chiral MOFs can be optimized for enantioseparation, but also the enantiomeric separation performance can be improved by optimizing the morphology and particle size of CMOF based stationary phases.…”