Dual-layer spectral CT improves image quality of multiphasic pancreas CT in patients with pancreatic ductal adenocarcinoma

Nagayama, Yasunori; Tanoue, Shota; Inoue, T; Oda, Shigeto; Nakaura, Takeshi; Utsunomiya, Daisuke; Yamashita, Yasuyuki

doi:10.1007/s00330-019-06337-y

Cited by 59 publications

(50 citation statements)

References 38 publications

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“…The aforementioned protocol was the routine protocol for preoperative staging of pancreatic cancer in our hospital. Theoretically and according to the literature, virtual monochromatic image with lower keV level had higher contrast-to-noise-ratio (CNR) and noise [15,16]. While only limited application of noise reduction software of ASiR in spectral imaging on CT750 HD scanner (GE Healthcare, Milwaukee Wis, USA) was approved by China Food and Drug Administration in 2016, the noise reduction technique could not be applied on the virtual monochromatic images lower than 60 keV in our CT scanner then.…”

Section: Ct Imaging Techniquementioning

confidence: 93%

Resectable pancreatic ductal adenocarcinoma: association between preoperative CT texture features and metastatic nodal involvement

Fang

Zhu

et al. 2020

Cancer Imaging

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Background: To explore the relationship between the lymph node status and preoperative computed tomography images texture features in pancreatic cancer. Methods: A total of 155 operable pancreatic cancer patients (104 men, 51 women; mean age 63.8 ± 9.6 years), who had undergone contrast-enhanced computed tomography in the arterial and portal venous phases, were enrolled in this retrospective study. There were 73 patients with lymph node metastases and 82 patients without nodal involvement. Four different data sets, with thin (1.25 mm) and thick (5 mm) slices (at arterial phase and portal venous phase) were analysed. Texture analysis was performed by using MaZda software. A combination of feature selection algorithms was used to determine 30 texture features with the optimal discriminative performance for differentiation between lymph node positive and negative groups. The prediction performance of the selected feature was evaluated by receiver operating characteristic (ROC) curve analysis. Results: There were 10 texture features with significant differences between two groups and significance in ROC analysis were identified. They were WavEnLH_s-2(wavelet energy with rows and columns are filtered with low pass and high pass frequency bands with scale factors 2) from wavelet-based features, 135dr_LngREmph (long run emphasis in 135 direction) and 135dr_Fraction (fraction of image in runs in 135 direction) from run length matrix-based features, and seven variables of sum average from coocurrence matrix-based features (SumAverg). The ideal cutoff value for predicting lymph node metastases was 270 for WavEnLH_s-2 (positive likelihood ratio 2.08). In addition, 135dr_ LngREmph and 135dr_Fraction were correlated with the ratio of metastatic to examined lymph nodes. Conclusions:Preoperative computed tomography high order texture features provide a useful imaging signature for the prediction of nodal involvement in pancreatic cancer.

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Section: Ct Imaging Techniquementioning

confidence: 93%

Resectable pancreatic ductal adenocarcinoma: association between preoperative CT texture features and metastatic nodal involvement

Fang

Zhu

et al. 2020

Cancer Imaging

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“…to most previous studies on adrenal imaging. Third, given that our results were retrieved from portal venous phase images acquired by using a vendor-specific dual-energy CT scanner, threshold values and diagnostic performance may not be directly applicable to images obtained with different protocols and dual-energy CT scanners (32)(33)(34)(35). Fourth, 11 patients had two adrenal lesions each, which could introduce clustering effects into the statistical analysis, although its possible effect may be limited by the small number of cases.…”

Section: Disclosures Of Conflicts Ofmentioning

confidence: 99%

Adrenal Adenomas versus Metastases: Diagnostic Performance of Dual-Energy Spectral CT Virtual Noncontrast Imaging and Iodine Maps

et al. 2020

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GASTROINTESTINAL IMAGINGG iven the extensive use of medical cross-sectional imaging, the incidental detection of adrenal lesions has concomitantly increased, occurring in approximately 5%-8% of patients undergoing CT (1-5). Although most incidental adrenal lesions are benign adenomas, the most common clinical dilemma has been the differentiation between adenomas and metastases, particularly among patients with a history of extra-adrenal malignancy (1-3). Because the presence of metastasis can affect treatment strategies and patient prognosis, accurate and noninvasive discrimination between the two entities is critical.Adrenal adenomas have two key CT imaging features: (a) low unenhanced attenuation reflecting intracytoplasmic fat content and (b) maximized contrast enhancement during the portal venous phase followed by rapid washout during the delayed phase (5)(6)(7)(8)(9)(10)(11)(12). Approximately 70% of adenomas can be diagnosed as lipid-rich adenoma based on unenhanced attenuation (10 HU) (5-8), whereas most lipid-poor adenomas (.10 HU) can be diagnosed based on the high washout rate calculated at multiphasic adrenal CT (7-12

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“…Subsequently, other authors have also shown improvements in image quality [50,51], lesion conspicuity [52][53][54], and evaluation of vascular involvement [55] using noiseoptimized lower energy (40-55 keV) monochromatic images and iodine maps [55,56].…”

Section: Accepted Manuscriptmentioning

confidence: 99%

Clinical Implementation of Dual-Energy CT for Gastrointestinal Imaging

Mileto

Ananthakrishnan

Morgan

et al. 2021

American Journal of Roentgenology

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The publication of this Accepted Manuscript is provided to give early visibility to the contents of the article, which will undergo additional copyediting, typesetting, and review before it is published in its final form. During the production process, errors may be discovered that could affect the content of the Accepted Manuscript. All legal disclaimers that apply to the journal pertain. The reader is cautioned to consult the definitive version of record before relying on the contents of this document.

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Dual-layer spectral CT improves image quality of multiphasic pancreas CT in patients with pancreatic ductal adenocarcinoma

Cited by 59 publications

References 38 publications

Resectable pancreatic ductal adenocarcinoma: association between preoperative CT texture features and metastatic nodal involvement

Resectable pancreatic ductal adenocarcinoma: association between preoperative CT texture features and metastatic nodal involvement

Adrenal Adenomas versus Metastases: Diagnostic Performance of Dual-Energy Spectral CT Virtual Noncontrast Imaging and Iodine Maps

Clinical Implementation of Dual-Energy CT for Gastrointestinal Imaging

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