Dual Kidney Transplant: A Single-Center Experience and Review of the Literature

Abstract

Objectives: Adult dual kidney transplant is a strategy to overcome the imbalance between limited nephron mass supplied from an older donor and a recipient with a metabolic request. Materials and Methods: In our report, we review the literature and present our single-center experience. From June 2007 until July 2012, nine hundred twenty-eight single and seventeen dual kidney transplants from deceased donors were performed. Results: The average donor was 71.5 ± 3.6 years of age with an average serum creatinine, creatinine clearance, and an average number of sclerotic glomeruli, 106.1 ± 44.2 µmol/L, 0.97 ± 0.37 mL/s, and 22.4 ± 14.2. Immediate graft function and acute rejection episodes were observed in 75% and 6% of patients. The overall patient survival rates at 1 and 2 years after transplant were 93%. The overall graft survival rates at 1 and 2 years were 88%. Conclusions: Previous studies and our single-center experience suggest that the dual transplant procedure may help improve results of kidney transplants from expanded criteria donors and extend the donor pool by using kidneys that would be discarded otherwise.

Safety of dual kidney transplantation compared to single kidney transplantation from expanded criteria donors: a single center cohort study of 39 recipients

“…39,41,42,53,54,[58][59][60][61][62][63][64]74,75) are comparable to ours (respectively 100% and 87.6%), as well as the recipient survival rates at 1 (89.7-100%, Ref. 38,39,41,42,44,52,[54][55][56]59,[61][62][63]75,77,78) and 3 years (80-97.5%, Ref. 39,41,42,54,[58][59][60][61][62][63]75), both at 97.4% in our series.…”

“…Other DKT series reported graft survival rates at 1 (82-100% Ref. 37,39,41,42,45,[52][53][54][55][56]59,[61][62][63]74,75,77,78) and 3 years (76-95%, Ref. 39,41,42,53,54,[58][59][60][61][62][63][64]74,75) are comparable to ours (respectively 100% and 87.6%), as well as the recipient survival rates at 1 (89.7-100%, Ref.…”

“…37,41,45,55,62,63), drained lymphoceles (5.1% vs 1.3-18.6%, Ref. 39,44,56,58,59,[61][62][63]65) and eventrations (7.7% vs 5-12.5%, Ref. 41,43,56,61,62).…”

“…39,41,43,45,[53][54][55][56][57][58][59], as well as the rates of ureteral stenoses (10.3% vs 0-11.1%, Ref. 38,39,41,43,56,[58][59][60][61][62][63], ureteral fistulas (2.6% vs 0-17% Ref. [37][38][39]41,[43][44][45]53,55,56,59,62,64,65), hematomas (15.4% vs 1-35.5%, Ref.…”

“…38,39,41,43,56,[58][59][60][61][62][63], ureteral fistulas (2.6% vs 0-17% Ref. [37][38][39]41,[43][44][45]53,55,56,59,62,64,65), hematomas (15.4% vs 1-35.5%, Ref. 37,41,45,55,62,63), drained lymphoceles (5.1% vs 1.3-18.6%, Ref.…”