Dual infection with pulmonary tuberculosis and <i>Lophomonas blattarum</i> in India

Verma, Santwana; Verma, Ghanshyam; Singh, Dig Vijay; Mokta, Jatinder; Negi, R. S.; Jhobta, Anupama; Kanga, Anil

doi:10.5588/ijtld.14.0513

Cited by 28 publications

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“…After the authors 2014 27 1 4 6 5 2 2 1 1 1 2 1 1 0 2015 16 0 1 2 4 3 4 0 0 0 1 0 0 1 2016 10 0 0 0 6 1 2 1 0 0 0 0 0 0 Total 53 1 5 8 15 6 8 2 1 1 3 1 1 1 searched the relevant papers, they found that the majority of these cases were from China, with a few cases being reported in Spain [6] and Peru [7]. One case of a patient having a dual infection with tuberculosis has been reported in India [11]. Unfortunately, L. blattarum infection presents with atypical symptoms, such as cough, sputum, and dyspnea [12]; all of these symptoms are common in other respiratory infections.…”

Section: Discussionmentioning

confidence: 99%

Pulmonary Infection with Lophomonas blattarum

Ding

Shen

2020

Indian J Pediatr

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Objective To describe the characteristics of Lophomonas blattarum infection in children based on a retrospective review of medical records data from Beijing Children's Hospital, Capital Medical University, China. Methods This study included 53 cases from July 2014 through December 2016. The data were tabulated and statistically analysed in a Microsoft Excel spreadsheet and SPSS 17.0. Results The average age of the 53 patients was 7.10 ± 0.56 years, and the male/female ratio was 3:2.3. The most common clinical manifestation was cough, and almost half of the patients had fever. Furthermore, all patients were treated with metronidazole and recovered. Conclusions For children who have had long-term respiratory symptoms, the possibility of Lophomonas blattarum infection should be ruled out. Metronidazole is effective in treating L. blattarum infection in children.

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Section: Discussionmentioning

confidence: 99%

Pulmonary Infection with Lophomonas blattarum

Ding

Shen

2020

Indian J Pediatr

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“…It indicates that Lophomonas enters the host regardless of the age, the sex, and the immune status. The reviewed publications show that there are new findings in countries like Turkey [ 3 ], Iran [ 10 ], India [ 11 ], and Chile [ 12 ]. Our study has shown that there are also cases in Peru; it may indicate that Lophomonas could be found in any country in it is being identified more frequently [ 2 , 4 , 8 , 13 ].…”

Section: Discussionmentioning

confidence: 99%

Lophomonas sp. in the upper and lower respiratory tract of patients from a hospital in Lambayeque, Peru: clinical case studies

Failoc‐Rojas

Iglesias-Osores

Silva-Díaz

2020

Respiratory Medicine Case Reports

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Infections with protozoans, mainly due to immunodeficiency, are common all over the world. However, pulmonary infections with protozoans are less frequent. Lophomonas sp. is a flagellated protozoan that lives in the gastrointestinal tract of some species of cockroaches. Some cases, that show the presence of Lophomonas in populations whose lungs are affected, have been reported. Case report: The medical records of nine patients were studied: seven adult patients and two pediatric patients who were in the Intensive Care Unit (ICU) and in the Neonatal Intensive Care Unit (NICU), respectively. The samples were taken from tracheal aspirations and bronchoalveolar lavages. The patients’ ages were between 9 and 95 years, and 60% of them were male. Some of the patients were healthy, a priori, and others were immunosuppressed. There were found three patients with neoplasia, two patients with diabetes mellitus and four patients with no systemic pathologies. It is concluded that Lophomonas sp. is a protozoa parasite which emerges from the upper and lower respiratory tract of hospitalized patients. However, its pathogenic role is still controversial in all cases, that's why it merits further study for its understanding and possible treatment.

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“…One case of a patient having dual infection with tuberculosis has been reported from India. [5] Lophomonas is classified under the supergroup Excavata, class Parabasalia. Trophozoites undergo cyst formation in adverse conditions and excyst into motile flagellates in favorable conditions, affecting protease receptors and tight junctions in the respiratory tract.…”

Section: Discussionmentioning

confidence: 99%

“…[5] We managed our patient with oral metronidazole 400 mg 8-hourly for 2 weeks, with good clinical response and resolution of peripheral eosinophilia. Severe cases may be treated with intravenous metronidazole 15 mg/kg/h followed by 7.5 mg/kg/6 h as maintenance.…”

Section: Discussionmentioning

confidence: 99%

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Lophomonas blattarum infection in immunocompetent patient

et al. 2016

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Lophomonas blattarum (L. blattarum) is a protozoan parasite living in intestinal tracts of termites and cockroaches. Chen and Meng from China repoted first case of pulmonary L. blattarum infection in 1993. 137 cases have only been reported in literature between 1993 to 2013. Majority of these infections occur in immunocompromised patients and have been reported from China. We report a case of this rare entity in an immunocompetent young Indian male.

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Dual infection with pulmonary tuberculosis and Lophomonas blattarum in India

Cited by 28 publications

References 0 publications

Pulmonary Infection with Lophomonas blattarum

Pulmonary Infection with Lophomonas blattarum

Lophomonas sp. in the upper and lower respiratory tract of patients from a hospital in Lambayeque, Peru: clinical case studies

Lophomonas blattarum infection in immunocompetent patient

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