“…Thereafter, Dr. Ilhan-Mutlu [2] gives us hope in her review "Dual immune checkpoint blockade in gastroe-D. Niedersüß-Beke, MD, MBA ( ) Center for Oncology, Hematology and Palliative Medicine, Klinik Ottakring, Montleartstr. 37, 1160 Vienna, Austria dora.niedersuess-beke@wienkav.at sophageal tumors: never say never", which shows that dual checkpoint inhibition can be also effective in gastroesophageal tumors, an entity in which checkpoint inhibition has so far not show as much benefit compared to other tumor entities.…”