Dual Functional Microcapsule based on Monodisperse Short PEG Amphiphile for Drug Encapsulation and Protein Affinity Controlled Release
Rohit N. Ketkar,
Paritosh Dey,
Triveni Sodnawar
et al.
Abstract:A short monodisperse poly(ethylene glycol) (PEG) and a neutral organic rotamer conjugate TEG‐BTA‐2 amphiphile was designed for the construction of a stimuli‐responsive switchable self‐assembled structure for drug encapsulation by noncovalent interaction and targeted controlled delivery. A short PEG, tetraethylene glycol (TEG) was covalently attached with a neutral organic rotamer benzothiazole dye (BTA‐2) affording the neutral TEG‐BTA‐2 (<500 D). The TEG‐BTA‐2 is self‐assembled into a microsphere in an aque… Show more
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