Dual-Energy X-Ray Dark-Field Material Decomposition

Sellerer, Thorsten; Tang, Ruizhi; Taphorn, Kirsten; Pfeiffer, Franz; Herzen, Julia

doi:10.1109/tmi.2020.3043303

Cited by 12 publications

(9 citation statements)

References 47 publications

(57 reference statements)

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“…The energy dependence parameter b for all materials decreases for increasing sensitivity. In general, a more quickly falling linear diffusion coefficient is expected for larger structures 19 , which is in agreement with our results (cf. Fig.…”

Section: Discussionsupporting

confidence: 93%

“…The linear diffusion coefficient can be approximated by a power-law where a gives the signal strength and b determines the energy dependence of the dark-field signal. The derivation of this approximation can be found in 19 . Although the power-law is derived for spheres, it was already demonstrated in simulation 20 and experiment 19 that this assumption also applies to complex homogeneous microstructures with no long-range order.…”

Section: Methodsmentioning

confidence: 99%

“…The derivation of this approximation can be found in 19 . Although the power-law is derived for spheres, it was already demonstrated in simulation 20 and experiment 19 that this assumption also applies to complex homogeneous microstructures with no long-range order.…”

Section: Methodsmentioning

confidence: 99%

“…Following these achievements, the next step is to combine spectral and dark-field imaging. In first studies, we have demonstrated that for instance materials with different sub-pixel microstructure can not only be differentiated, but also qualitatively ranged regarding their microstructure size with spectral X-ray dark-field imaging 18 , followed by quantitative material decomposition which we successfully transferred from the absorption channel to the dark-field channel 19 . Latest, we proposed an application of spectral X-ray dark-field imaging for thorax radiography, where a direct differentiation of pathological changes, such as emphysema and fibrosis, in the human lung parenchyma was enabled with spectral X-ray dark-field imaging, which is not possible in single-spectrum conventional dark-field radiography 20 .…”

Section: Introductionmentioning

confidence: 99%

“…Aiming for material-selective information, analysis methods for dual-energy data require either a calibration routine 19 or prior knowledge of the behavior of the observed signal with the X-ray energy. In the case of the attenuation contrast, the attenuation coefficient is a well-known material-specific property and can be found in several databases (e.g.…”

Section: Introductionmentioning

confidence: 99%

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Spectral X-ray dark-field signal characterization from dual-energy projection phase-stepping data with a Talbot-Lau interferometer

Taphorn

Kaster

Sellerer

et al. 2023

Sci Rep

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Material-selective analysis of spectral X-ray imaging data requires prior knowledge of the energy dependence of the observed signal. Contrary to conventional X-ray imaging, where the material-specific attenuation coefficient is usually precisely known, the linear diffusion coefficient of the X-ray dark-field contrast does not only depend on the material and its microstructure, but also on the setup geometry and is difficult to access. Here, we present an optimization approach to retrieve the energy dependence of the X-ray dark-field signal quantitatively on the example of closed-cell foams from projection data without the need for additional hardware to a standard grating-based X-ray dark-field imaging setup. A model for the visibility is used to determine the linear diffusion coefficient with a least-squares optimization. The comparison of the results to spectrometer measurements of the linear diffusion coefficient suggests the proposed method to provide a good estimate for the energydependent dark-field signal.

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Section: Discussionsupporting

confidence: 93%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Spectral X-ray dark-field signal characterization from dual-energy projection phase-stepping data with a Talbot-Lau interferometer

Taphorn

Kaster

Sellerer

et al. 2023

Sci Rep

Self Cite

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Direct x-ray scattering signal measurements in edge-illumination/beam-tracking imaging and their interplay with the variance of the refraction signals

Buchanan,

Cipiccia,

Peiffer

et al. 2023

Applied Physics Reviews

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X-ray dark-field or ultra-small angle scatter imaging has become increasingly important since the introduction of phase-based x-ray imaging and is having transformative impact in fields such as in vivo lung imaging and explosives detection. Here, we show that dark-field images acquired with the edge-illumination method (either in its traditional double mask or simplified single mask implementation) provide a direct measurement of the scattering function, which is unaffected by system-specific parameters such as the autocorrelation length. We show that this is a consequence both of the specific measurement setup and of the mathematical approach followed to retrieve the dark-field images. We show agreement with theoretical models for datasets acquired both with synchrotron and laboratory x-ray sources. We also introduce a new contrast mechanism, the variance of refraction, which is extracted from the same dataset and provides a direct link with the size of the scattering centers. We show that this can also be described by the same theoretical models. We study the behavior of both signals vs key parameters such as x-ray energy and scatterer radius. We find this allows quantitative and direct scattering measurements during imaging, with implications in all fields where dark-field imaging is used.

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Tri-directional x-ray phase contrast multimodal imaging using one hexagonal mesh modulator

Tao,

Tian,

Bai

et al. 2023

Phys. Med. Biol.

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Objective. X-ray phase contrast imaging is a promising technique for future clinical diagnostic as it can provide enhanced contrast in soft tissues compared to traditional X-ray attenuation-contrast imaging. However, the strict requirements on the X-ray coherence and the precise alignment of optical elements limit its applications towards clinical use. To solve this problem, mesh-based X-ray phase contrast imaging method with one hexagonal mesh is proposed for easy alignment and better image visualization. Approach. The mesh produces structured illuminations and the detector captures its distortions to reconstruct the absorption, differential phase contrast (DPC) and dark-field (DF) images of the sample. In this work, we fabricated a hexagonal mesh to simultaneously retrieve DPC and DF signals in three different directions with single shot. A phase retrieval algorithm to obtain artifacts-free phase from DPC images with three different directions is put forward and false color dark-field image is also reconstructed with tri-directional images. Mesh-shifting method based on this hexagonal mesh modulator is also proposed to reconstruct images with better image quality at the expense of increased dose. Main results. In numerical simulations, the proposed hexagonal mesh outperforms the traditional square mesh in image evaluation metrics performance and false color visualization with the same radiation dose. The experimental results demonstrate its feasiblity in real imaging systems and its advantages in quantitive imaging and better visualization. The proposed hexagonal mesh is easy to fabricate and can be successfully applied to X-ray source with it spot size up to 300μm. Significance. This work opens new possibilities for quantitative X-ray non-destructive imaging and may also be instructive for research fields such as X-ray structured illumination microscopy (SIM), X-ray spectral imaging and X-ray phase contrast and dark-field computed tomography (CT).

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Dual-Energy X-Ray Dark-Field Material Decomposition

Cited by 12 publications

References 47 publications

Spectral X-ray dark-field signal characterization from dual-energy projection phase-stepping data with a Talbot-Lau interferometer

Spectral X-ray dark-field signal characterization from dual-energy projection phase-stepping data with a Talbot-Lau interferometer

Direct x-ray scattering signal measurements in edge-illumination/beam-tracking imaging and their interplay with the variance of the refraction signals

Tri-directional x-ray phase contrast multimodal imaging using one hexagonal mesh modulator

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