Dual-Energy CT: Balance Between Iodine Attenuation and Artifact Reduction for the Evaluation of Head and Neck Cancer

Nair, Jaykumar Raghavan; DeBlois, F; Ong, Thomas; Dević, Slobodan; Tomic, Nada; Bekerat, Hamed; Rosenbloom, Lorne; Sultanem, Khalil; Forghani, Reza

doi:10.1097/rct.0000000000000617

Cited by 18 publications

(3 citation statements)

References 15 publications

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“…It is caused by the photon starvation effect and beam hardening effect. Some researchers have investigated direct in the ability to remove metal artifacts of dual-energy mode CT acquisitions with monochromatic imaging results (11)(12)(13)(14)(15)(16)(17). Magarelli et al (18) performed the study that assessed image quality of dualenergy CT to reduce metal artifacts in subjects with knee and hip prostheses.…”

Section: Discussionmentioning

confidence: 99%

Comparison of Image Quality and Radiation Dose Between Single-Energy and Dual-Energy Images for the Brain With Stereotactic Frames on Dual-Energy Cerebral CT

et al. 2022

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BackgroundPreoperative stereotactic planning of deep brain stimulation (DBS) using computed tomography (CT) imaging in patients with Parkinson's disease (PD) is of clinical interest. However, frame-induced metal artifacts are common in clinical practice, which can be challenging for neurosurgeons to visualize brain structures.ObjectivesTo evaluate the image quality and radiation exposure of patients with stereotactic frame brain CT acquired using a dual-source CT (DSCT) system in single- and dual-energy modes.Materials and MethodsWe included 60 consecutive patients with Parkinson's disease (PD) and randomized them into two groups. CT images of the brain were performed using DSCT (Group A, an 80/Sn150 kVp dual-energy mode; Group B, a 120 kVp single-energy mode). One set of single-energy images (120 kVp) and 10 sets of virtual monochromatic images (50–140 keV) were obtained. Subjective image analysis of overall image quality was performed using a five-point Likert scale. For objective image quality evaluation, CT values, image noise, signal-to-noise ratio (SNR), and contrast-to-noise (CNR) were calculated. The radiation dose was recorded for each patient.ResultsThe mean effective radiation dose was reduced in the dual-energy mode (1.73 mSv ± 0.45 mSv) compared to the single-energy mode (3.16 mSv ± 0.64 mSv) (p < 0.001). Image noise was reduced by 46–52% for 120–140 keV VMI compared to 120 kVp images (both p < 0.01). CT values were higher at 100–140 keV than at 120 kVp images. At 120–140 keV, CT values of brain tissue showed significant differences at the level of the most severe metal artifacts (all p < 0.05). SNR was also higher in the dual-energy mode 90–140 keV compared to 120 kVp images, showing a significant difference between the two groups at 120–140 keV (all p < 0.01). The CNR was significantly better in Group A for 60–140 keV VMI compared to Group B (both p < 0.001). The highest subjective image scores were found in the 120 keV images, while 110–140 keV images had significantly higher scores than 120 kVp images (all p < 0.05).ConclusionDSCT images using dual-energy modes provide better objective and subjective image quality for patients with PD at lower radiation doses compared to single-energy modes and facilitate brain tissue visualization with stereotactic frame DBS procedures.

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Section: Discussionmentioning

confidence: 99%

Comparison of Image Quality and Radiation Dose Between Single-Energy and Dual-Energy Images for the Brain With Stereotactic Frames on Dual-Energy Cerebral CT

et al. 2022

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“…VMIs with low keV can increase the image contrast and thus compensate low contrast medium concentrations (13)(14)(15). VMIs with high keV allow for the reduction of metal artefacts, e.g., of dental implants (16)(17)(18).…”

Section: Original Articlementioning

confidence: 99%

Dual-energy computed tomography of the neck—optimizing tube current settings and radiation dose using a 3D-printed patient phantom

Diekhoff

Scheel

Kress

et al. 2021

Quant Imaging Med Surg

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Background: Dual-energy computed tomography (DECT) is increasingly used in studies and clinical practice. However, the best protocol is controversially discussed and whether it exhibits more radiation exposure compared to conventional protocols. Thus, the purpose of the study was to determine optimal tube current settings for DECT in a 3D-printed anthropomorphic phantom of the neck.Methods: A 3D-printed iodinated ink based phantom of a contrast enhanced CT of the neck was imaged.Six dual-energy multi-detector computed tomography scans were performed with six different tube currents (80 kVp: 30-400 mAs; 135 kVp: 5-160 mAs). 120 virtual blended images (VBIs) and 66 virtual monochromatic images (VMIs) were reconstructed and 12 regions of interest (bilaterally: common carotid arteries, subcutaneous soft tissue, mandibular bone, sternocleidomastoid muscle, submandibular gland, and mid-image: vertebral body of C2 and pharyngeal space) in six consecutive slices resulting in 96 measurements per scan were performed. Hounsfield units and signal-and contrast-to-noise ratio were compared to singleenergy computed tomography as standard of reference.Results: VBIs overestimated the Hounsfield units (P<0.0001). Optimal dual-energy scanning parameters resulted in 120% (100 kVe: 51.2 vs. 61.7 and 65.2, for signal and contrast-to-noise ratio, respectively; 120 kVe: 60.8 vs. 72.1 vs. 128.3) of the radiation exposure with about 80% of the signal/contrast-to-noise ratio of the corresponding single-energy images. However, optimal weighting of tube currents for both voltages depended on the desired reconstruction.Conclusions: Dual-energy protocols apply an estimated 120% of the single-energy radiation exposure and result in approximately 80% of the image quality. Tube current settings should be adapted to the desired information.

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“…Уменьшение выраженности артефактов позволило улучшить визуализацию мягкого нёба и щёк (например, CI/VMI200кЭв: 2(1-4)/3(1-5) и ещё 2(1-5)/3(1-5), р ≤0,05). В целом виртуальные моноэнергетические изображения, полученные в ходе постпроцессинга объёмов ДЭКТ, уменьшают выраженность артефактов от зубных имплантатов, улучшая диагностику окружающих мягких тканей [28] оценки рака головы и шеи [29]. Это подтверждают данные исследования E. Liao [30], согласно которым ДЭКТ способствует улучшению визуализации области головы, шеи и позвоночника на фоне артефактов от металлических имплантатов.…”

Section: A R T I C L E I N P R E S Sunclassified

Dual-energy computed tomography for head and neck cancer

Petrovichev

Neklyudova

Sinitsyn

et al. 2021

Digital Diagnostics

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The article provides a review of publications by the diagnosis of head and neck cancer using dual-energy computed tomography (DECT), the results of qualitative and quantitative analysis of the data were obtained by the DECT method with intravenous contrast enhancement for tumors of this localization, shows the importance of constructing iodine maps for obtaining additional diagnostic information. Including the article is described aspects of improving visualization of the oropharyngeal region against the background of artifacts from dental implants. A number of research articles highlight the current state of the issue and the role of post-processing of raw data DECT, obtaining a range of monochromatic images of tumor and other pathological changes in the head and neck region in the article. Several learned treatises were also reflected, in which DECT with intravenous contrast enhancement and routine computed tomography in terms of reducing radiation exposure to patients were compared, in particular, due to possibility of obtaining virtual native diagnostic images from a contrast series of DECT volumes during post-processing. This review, in addition to latest relevant scientific data, also includes references to works, that highlight the history of the development of DECT as the method. The physical principles underlying DECT and the prospects for the development of the method are briefly represented.

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Dual-Energy CT: Balance Between Iodine Attenuation and Artifact Reduction for the Evaluation of Head and Neck Cancer

Abstract: High energy VMIs less than 100 keV can achieve modest artifact reduction while preserving sufficient iodine attenuation and could represent a useful additional reconstruction for evaluation of head and neck cancer.

Cited by 18 publications

References 15 publications

Comparison of Image Quality and Radiation Dose Between Single-Energy and Dual-Energy Images for the Brain With Stereotactic Frames on Dual-Energy Cerebral CT

Comparison of Image Quality and Radiation Dose Between Single-Energy and Dual-Energy Images for the Brain With Stereotactic Frames on Dual-Energy Cerebral CT

Dual-energy computed tomography of the neck—optimizing tube current settings and radiation dose using a 3D-printed patient phantom

Dual-energy computed tomography for head and neck cancer

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