Dual-colored carbon dot encapsulated metal-organic framework for ratiometric detection of glutathione

The Construction and Testing of an Amperometric Biosensor for Oxidized Glutathione with Glutathione Reductase Immobilized on Reduced Graphene Oxide Paper Modified with Cobalt Sulphur

“…High concentration of GSSG causes diseases such as asthma, human immunodeficiency virus type 1 infection, and chronicle renal failure [12] . Therefore, determining the GSH, [13] GSSG [14] or GSH/GSSG ratio [15] is an important biomarker.…”

Recent Progress in Luminous Particle‐Encapsulated Host–Guest Metal‐Organic Frameworks for Optical Applications

“…A ratiometric luminescent sensor for selectively detecting GSH was prepared by the encapsulating of blue-emitting CDs (BCDs) and yellow emitting CDs (YCDs) into the zeolitic imidazolate framework (B/YCDs@ZIF-8). [246] The luminescence of BCDs of the B/YCDs@ZIF-8 was quenched while the luminescence of the YCDs was enhanced upon immersion of the B/YCDs@ ZIF-8 composite in a Cu 2+ solution, which was attributed to the coordination of Cu 2+ ions with COOH groups/NH 2 group on the surface of BCDs/YCDs. After adding GSH to the Cu 2+ -BYCDs@ZIF-8 system, the fluorescence intensity of both CDs could be well recovered due to the strong interaction between GSH and Cu 2+ .…”

“…[140] Furthermore, yellow-emitting and blue-emitting CDs were encapsulated in ZIF-8 to prepare a dual-emission composite BYCDs@ZIF-8. [150] Nevertheless, the inherent large size of CDs requires MOFs with a large aperture for effective encapsulation, which limits the selection range of MOF hosts.…”

Centri‐Voltammetric GSH Detection with PDI‐C4SH as a Carrier Material

“…Among these techniques, electrochemical methods are widely used for the determination of many molecules since they have advantages like being economical, simple, and accurate. [29][30][31][32] Various modifiers such as silica nanoparticles, [33] carbon dots [34] and βcyclodextrin, [35,36] have been utilized for GSH detection in order to lower the mandatory over potential for GSH oxidation. [37] Also different electroanalytical techniques like amperometric, [38,39] advanced voltammetric techniques like square-wave voltammetry, [40] differential pulse voltammetry (DPV), [41] cyclic voltammetry [42] stripping voltammetry [43] and hydrodynamic voltammetry [44] were tested for the increment of efficacy of electrochemical detection methods for GSH.…”