Dual and Multi-Emission Hybrid Micelles Realized through Coordination-Driven Self-Assembly

Abstract

Building novel functional nanomaterials with a polymer is one of the most dynamic research fields at present. Here, three amphiphilic block copolymers of 8-hydroxyquinoline derivative motifs (MQ) with excellent coordination function were synthesized by Reversible Addition-Fragmentation Chain Transfer Polymerization (RAFT) polymerization. The coordination micelles were prepared through the self-assembly process, which the MQ motifs were dispersed in the hydrophobic polystyrene (PSt) blocks and hydrophilic Poly(N-isopropylacrylamide (PNIPAM)) blocks, respectively. The dual-emission micelles including the intrinsic red light emission of quantum dots (QDs) and the coordination green light emission of Zn2+-MQ complexes were built by introducing the CdSe/ZnS and CdTe/ZnS QDs in the core and shell precisely in the coordination micelles through the coordination-driven self-assembly process. Furthermore, based on the principle of three primary colors that produce white light emission, vinyl carbazole units (Polyvinyl Carbazole, PVK) with blue light emission were introduced into the hydrophilic PNIPAM blocks to construct the white light micelles that possess special multi-emission properties in which the intrinsic red light emission of QDs, the coordination green light of Zn2+-MQ complexes, and the blue light emission of PVK were synergized. The dual and multi-emission hybrid micelles have great application prospects in ratiometric fluorescent probes and biomarkers.

Nanoengineering with RAFT polymers: from nanocomposite design to applications

“…One way of circumventing this issue is to use macromolecular ligands, which can be easily prepared via RAFT polymerization. Here, a multiply-binding copolymer design has been proven to be very effective: one type of monomer contains an anchoring group for QD binding, such as thiol, 164 carboxyl, 146,147 imidazole 112,188,189 and 8-hydroxyquinoline 241 moieties. Another part of the polymer adjusts dispersibility and provides additional properties.…”