Dual‐Action Flexible Antimicrobial Material: Switchable Self‐Cleaning, Antifouling, and Smart Drug Release

Děkanovský, Lukáš; Elashnikov, Roman; Kubiková, Markéta; Vokatá, Barbora; Švorčı́k, Václav; Lyutakov, Oleksiy

doi:10.1002/adfm.201901880

Cited by 65 publications

(48 citation statements)

References 45 publications

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“…[ 37 ] An effective strategy to solve the problem is to develop a switchable superwettable surface. For example, Deˇkanovský et al [ 38 ] reported a superhydrophobic and switchable material surface based on a highly stretchable silicon polymer doped with polypyrrole. In general, this surface underwater could form an air gap.…”

Section: Progress In Surface Modifications For Preventing Bacterial Adhesionmentioning

confidence: 99%

Surface Design for Antibacterial Materials: From Fundamentals to Advanced Strategies

et al. 2021

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Healthcare-acquired infections as well as increasing antimicrobial resistance have become an urgent global challenge, thus smart alternative solutions are needed to tackle bacterial infections. Antibacterial materials in biomedical applications and hospital hygiene have attracted great interest, in particular, the emergence of surface design strategies offer an effective alternative to antibiotics, thereby preventing the possible development of bacterial resistance. In this review, recent progress on advanced surface modifications to prevent bacterial infections are addressed comprehensively, starting with the key factors against bacterial adhesion, followed by varying strategies that can inhibit biofilm formation effectively. Furthermore, "super antibacterial systems" through pre-treatment defense and targeted bactericidal system, are proposed with increasing evidence of clinical potential. Finally, the advantages and future challenges of surface strategies to resist healthcare-associated infections are discussed, with promising prospects of developing novel antimicrobial materials.

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Section: Progress In Surface Modifications For Preventing Bacterial Adhesionmentioning

confidence: 99%

Surface Design for Antibacterial Materials: From Fundamentals to Advanced Strategies

et al. 2021

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“…These methods have a great disadvantage: they present some difficulties in the reproductibility of the process of surface modification, in particular in the case of the polymerization process of the MPC monomer. Alternative methods have been recently developed by use of active surfaces with electrically switchable hydrophobic/hydrophilic wettability targeted to prevent bacterial attachment and biofilm formation [59,60].…”

Section: Introductionmentioning

confidence: 99%

Controlled structure and hydrophilic property of polymethylhydrosiloxane thin films attached on silicon support and modified with phosphorylcholine group

2020

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Thin films of crosslinked polymethylhydrosiloxane (PMHS) are grafted on silica using sol-gel process allowing subsequent coupling of molecules by hydrosilylation grafting to Si-H groups.The aim was to fabricate stable polysiloxane film on solid supports with well-characterized functionalities and surface properties for various applications. The pristine PMHS surface was modified with phosphorylcholine group by reaction at room temperature or 40 °C catalyzed by Karsted's catalyst with a phospholipid molecule containing linoleoyl chains to form hydrophilic surfaces as a model. The purpose was to characterize precisely the structure and composition of virgin and treated PMHS films in relation with the wetting properties by using IR and X-ray photoelectron spectroscopies (XPS). The surface properties were studied by pure water contact *Manuscript Click here to view linked References 2 angle measurements in air by using sessile drops and captive bubbles, atomic force microscopy, and scanning electron microscopy. The modified surfaces are highly hydrophilic with contact angle varying from 40 to 0°. Analysis of the composition of the surface showed that the reaction of linoleoyl chains gives the 2:1 (Si:phospholipid) hydrosilylation adducts resultant from one fold addition of methylhydrosilane on each linoleoyl chain. The graft yield in terms of molecular percentage determined by XPS in various conditions was correlated in good agreement with wetting properties and previous protein adsorption measurements for comparison purpose.

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“…As a result, the precise control of the surface wetting is achieved, with related on-demand introduction of superhydrophobicity or water repellence. With such surface designs, smart activation of surface self-cleaning and bacterial repulsion functionality can be achieved [140][141][142]. In ref.…”

Section: Electro-responsive Coatingsmentioning

confidence: 99%

Physically Switchable Antimicrobial Surfaces and Coatings: General Concept and Recent Achievements

et al. 2021

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Bacterial environmental colonization and subsequent biofilm formation on surfaces represents a significant and alarming problem in various fields, ranging from contamination of medical devices up to safe food packaging. Therefore, the development of surfaces resistant to bacterial colonization is a challenging and actively solved task. In this field, the current promising direction is the design and creation of nanostructured smart surfaces with on-demand activated amicrobial protection. Various surface activation methods have been described recently. In this review article, we focused on the “physical” activation of nanostructured surfaces. In the first part of the review, we briefly describe the basic principles and common approaches of external stimulus application and surface activation, including the temperature-, light-, electric- or magnetic-field-based surface triggering, as well as mechanically induced surface antimicrobial protection. In the latter part, the recent achievements in the field of smart antimicrobial surfaces with physical activation are discussed, with special attention on multiresponsive or multifunctional physically activated coatings. In particular, we mainly discussed the multistimuli surface triggering, which ensures a better degree of surface properties control, as well as simultaneous utilization of several strategies for surface protection, based on a principally different mechanism of antimicrobial action. We also mentioned several recent trends, including the development of the to-detect and to-kill hybrid approach, which ensures the surface activation in a right place at a right time.

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Dual‐Action Flexible Antimicrobial Material: Switchable Self‐Cleaning, Antifouling, and Smart Drug Release

Cited by 65 publications

References 45 publications

Surface Design for Antibacterial Materials: From Fundamentals to Advanced Strategies

Surface Design for Antibacterial Materials: From Fundamentals to Advanced Strategies

Controlled structure and hydrophilic property of polymethylhydrosiloxane thin films attached on silicon support and modified with phosphorylcholine group

Physically Switchable Antimicrobial Surfaces and Coatings: General Concept and Recent Achievements

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