“…a reduction in the severity of either (or both as in Keshavan et al's sample) would obscure this relationship by decreasing the signal-to-noise ratio. Incidentally, in a larger sample of 40 medication-free schizophrenic inpatients (Mazzara et al 1989), we continue to observe a 35% rate of nonsuppression (14 of 40) and a relationship between negative symptom severity and postdexamethasone cortisol (r = 0.38. 17 '.. 0.02).…”