Dry mouth and denture plaque microflora in complete denture and palatal obturator prosthesis wearers

Abstract

It was concluded that palatal obturator prosthesis wearers with a dry mouth have greater colonisation by Candida spp. and Staphylococcus spp. than do complete denture wearers.

Impact of Type and Duration of Application of Commercially Available Oral Moisturizers on Their Antifungal Effects

“…These results indicate that the MIC of AMPH‐B against C. albicans varies depending upon patients’ systemic conditions. Dry mouth occurs among medically compromised oral cancer patients undergoing surgical treatment, radiotherapy, and chemotherapy . In the present study, mixing liquid and gel moisturizers increased the size of the growth‐inhibitory zones to the same level as those of AMPH‐B at two concentrations (1.25 and 2.5 μg/ml).…”

“…These drugs, however, cause adverse side effects such as hyperhidrosis and dyspepsia, so that oral moisturizers are frequently required . In the present study, we focused on the antifungal effects of oral moisturizers to reduce the risk of C. albicans infection, which is common among dry mouth patients. One in vitro study reported that although oral moisturizers exerted an antibacterial effect on Staphylococcus aureus , no antifungal effect on C. albicans was observed .…”

“…Several studies have reported that in addition to increasing the incidence of dental caries and denture ulcers, 1,2 dry mouth causes an increase in the presence and number of Candida albicans organisms in the oral cavity and on the mucosal surface of dentures. 1,3,4 Because C. albicans coaggregates with highly pathogenic bacteria, it can serve as a reservoir for bacteria 5,6 and may cause denture stomatitis, oral candidiasis, and aspiration pneumonia. 3,5,6 To avoid the growth of drug-resistant strains, long-term use of antifungal drugs should be minimized when treating such conditions.…”

An antifungal coating for dental silicones composed of chlorhexidine nanoparticles

“…A greater proportion of obturators exhibit bacterial and fungal colonisation than dentures, and these obturators are colonised by a larger number of different species than dentures. 14,15 Obturators fabricated from silicone attract greater microbial colonisation than those made from titanium. 6 Obturators can become superinfected as C. albicans and other microorganisms from the nose and mouth penetrate into the material and cause material degradation, as well as acting as a reservoir for microbes, leading to chronic local or even systemic infection and inflammation.…”

Impact of Types of Moisturizer and Humidity on the Residual Weight and Viscosity of Liquid and Gel Oral Moisturizers

“…In addition, the prevalence of Candid a spp. and Staphylococcus spp., which are the causative bacteria of aspiration pneumonia, is significantly higher in dry mouth patients than in those without dry mouth . Therefore, proper response is fundamental for dry mouth patients to avoid the risk of systemic infection.…”