Drugs that reduce the motility of the gastrointestinal tract

Abstract

Spastic reactions of smooth muscles of visceral organs play an important role in the pathogenesis of many diseases, the main drugs for relief of which are antispasmodic drugs. The article describes in detail the mechanisms of development of spastic abdominal pain and possible ways to correct it. The mechanisms of influence of the main myotropic antispasmodics on the gastrointestinal tract are given. Particular attention is paid to the peculiarities of pharmacodynamics, pharmacokinetics, listed indications, contraindications, features of drug interaction.

Modern management of patients with intestinal diseases. Analysis of clinical cases

“…На цю патологію страждає 10-15 % дорослої популяції. У розвитку СПК значну роль відіграє порушення взаємозв'язку «кишечник -головний мозок» [7].…”