DRUGS OF ABUSE | Urine

Huang, Minwei; Chang, B.-L.; Liao, Chia-Hung; Liu, R.H.

doi:10.1006/rwfs.2000.0491

Cited by 1 publication

(2 citation statements)

References 2 publications

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“…In plasma, after oral administration of methamphetamine, concentrations of the metabolite amphetamine are lower than methamphetamine with the 24-h area under the curve (AUC 24 ) for amphetamine showing a typical doseresponse relationship (169,171,181). As urine is the primary mechanism of elimination following exposure to amphetamines, it is most commonly used for the purpose of assessing and quantifying workplace exposure, driving related offences and criminal cases (181)(182)(183). Analyses of urine for exposure to methamphetamine are only considered positive if the levels are above a pre-determined cut-off limit and the metabolite amphetamine is also detected.…”

Section: Blood and Urinementioning

confidence: 99%

“…Analyses of urine for exposure to methamphetamine are only considered positive if the levels are above a pre-determined cut-off limit and the metabolite amphetamine is also detected. The cut-off limit is above the detection limit and allows for low levels to be present either directly or as metabolites from prescribed medicines (182,184). Methamphetamine and amphetamine concentrations in urine are generally higher than reported in blood plasma and, while rapidly cleared from the body, can remain quantifiable for longer periods of time after multiple doses, with detections reported after 46-196 h (181).…”

Section: Blood and Urinementioning

confidence: 99%

See 1 more Smart Citation

Exposures associated with clandestine methamphetamine drug laboratories in Australia

Wright

Edwards

Walker

2016

Reviews on Environmental Health

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AbstractThe clandestine manufacture of methamphetamine in residential homes may represent significant hazards and exposures not only to those involved in the manufacture of the drugs but also to others living in the home (including children), neighbours and first responders to the premises. These hazards are associated with the nature and improper storage and use of precursor chemicals, intermediate chemicals and wastes, gases and methamphetamine residues generated during manufacture and the drugs themselves. Many of these compounds are persistent and result in exposures inside a home not only during manufacture but after the laboratory has been seized or removed. Hence new occupants of buildings formerly used to manufacture methamphetamine may be unknowingly exposed to these hazards. Children are most susceptible to these hazards and evidence is available in the literature to indicate that these exposures may result in immediate and long-term adverse health effects. The assessment of exposure within the home can be undertaken by measuring contaminant levels or collecting appropriate biological data from individuals exposed. To gain a better understanding of the available data and key issues associated with these approaches to the characterisation of exposure, a review of the published literature has been undertaken.

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Section: Blood and Urinementioning

confidence: 99%

Section: Blood and Urinementioning

confidence: 99%