Drugs of Abuse Testing

Dasgupta, Amitava; Wahed, Amer

doi:10.1016/b978-0-12-407821-5.00016-4

Cited by 2 publications

(2 citation statements)

References 15 publications

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“…Furthermore, other drugs such as bupropion (its metabolites), trazodone, labetalol and doxepin can also cause false positive test results. Finally, available data confirmed results of the present work, where it was reported that non-steroidal anti-inflammatory drugs, pantoprazole and efavirenz can give false positive immunoassay results for tetrahydrocannabinol (Dasgupta and Wahed, 2014).…”

Section: Resultssupporting

confidence: 91%

Screening for Abused Drugs in Donated Blood

Abdou¹,

Aldosari²,

Rayes³

et al. 2015

J. of Pharmacology and Toxicology

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Donor blood represents one of the most important sources of therapeutic preparations required for various cases necessitating transfusions of plasma or erythrocytes. While, thorough screening tests for, for example, syphilis and other infectious agents are conducted (as a routine test), other analytical tests aiming at the detection of drug residues are rare (if at all) performed. The present study was designed-as a preliminary study-to discover drugs of abuse in blood in donating King Abdul-Aziz Hospital (Makkah, Saudi Arabia). A total of 300 EDTA plasma samples (approximately 1.5 mL each) was obtained from a King Abdul-Aziz Hospital blood bank from voluntary blood donors after regular whole blood donation. Immediately after sampling, the plasma was separated in a centrifuge, transferred to a 2 mL Eppendorf tube and frozen until analysis. All donors were males; in the preliminary test, 28 cases (9.3%) were positive for one of screened substance (1 case; 0.3% were positive for amphetamine, 7 cases (2.3%) were positive for tricyclic antidepressants TCA and 20 cases (6.7%) were positive for tetrahydrocannabinol (THC). On the second screen, confirmed cases were 20 cases (6.7%), 1 case (0.3%) was positive for amphetamine, 2 cases (0.7%) were positive for TCA and 17 cases (5.7%). Positive cases were significantly younger than negative cases (25.80±2.58 vs. 27.34±3.08 years, respectively). The present study sheds light on the importance of screening blood and blood products in blood banks for commonly abused drugs, besides regular checkup for infectious diseases. It is advised to put this step as a routine in blood screening as much as the facilities permit to do so.

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Section: Resultssupporting

confidence: 91%

Screening for Abused Drugs in Donated Blood

Abdou¹,

Aldosari²,

Rayes³

et al. 2015

J. of Pharmacology and Toxicology

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“…Recently semiconductor nanowires have attracted great attention due to their unique physical properties and potential applications in nanoelectronics, optoelectronics, and quantum electronics. [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17] With advances in the materials technology, highquality semiconductor nanowire have been obtained through, for instance, molecular-beam epitaxy, [18][19][20] metal-organic vapor phase epitaxy, [21][22][23] and chemical vapor deposition. [24][25][26][27][28][29] Due to their well organized crystal structures, relatively high carrier mobilities, small cross sections, and strong quantum confinement effects, III-V semiconductor nanowires have been employed to construct field-effect transistors, [30][31][32][33] infrared photodetectors, 34,35 light emission diodes, 36,37 thermal electrical devices, 38,39 laser devices, 40,41 solar cells, [42][43][44]…”

Section: Introductionmentioning

confidence: 99%

k.p theory of freestanding narrow band gap semiconductor nanowires

Luo

Liao

2016

AIP Advances

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We report on a theoretical study of the electronic structures of freestanding nanowires made from narrow band gap semiconductors GaSb, InSb and InAs. The nanowires are described by the eight-band k.p Hamiltonians and the band structures are computed by means of the finite element method in a mixture basis consisting of linear triangular elements inside the nanowires and constrained Hermite triangular elements near the boundaries. The nanowires with two crystallographic orientations, namely the [001] and [111] orientations, and with different cross-sectional shapes are considered. For each orientation, the nanowires of the three narrow band gap semiconductors are found to show qualitatively similar characteristics in the band structures. However, the nanowires oriented along the two different crystallographic directions are found to show different characteristics in the valence bands. In particular, it is found that all the conduction bands show simple, good parabolic dispersions in both the [001]- and [111]-oriented nanowires, while the top valence bands show double-maximum structures in the [001]-oriented nanowires, but single-maximum structures in the [111]-oriented nanowires. The wave functions and spinor distributions of the band states in these nanowires are also calculated. It is found that significant mixtures of electron and hole states appear in the bands of these narrow band gap semiconductor nanowires. The wave functions exhibit very different distribution patterns in the nanowires oriented along the [001] direction and the nanowires oriented along the [111] direction. It is also shown that single-band effective mass theory could not reproduce all the band state wave functions presented in this work.Comment: 17 pages, 19 figure

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Drugs of Abuse Testing

Cited by 2 publications

References 15 publications

Screening for Abused Drugs in Donated Blood

Screening for Abused Drugs in Donated Blood

k.p theory of freestanding narrow band gap semiconductor nanowires

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