Drugs in Cardiac Failure

Lye, M.

doi:10.1007/978-94-009-4890-7_2

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1995

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“…After more than 200 years of experience with cardiac glycosides, digoxin remains the first choice for patients with heart failure and rapid atrial fibrillation. With sinus rhythm or slow fibrillation there is concern that the risks will outweigh benefit, particularly in elderly patients 24 . Digoxin has a narrow therapeutic window, and potentially serious intoxication is more prevalent in elderly patients.…”

Section: Prevalencementioning

confidence: 99%

Heart Failure in the Elderly Patient

Valácio

Lye

1995

Int J Clinical Practice

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SUMMARY Both prevalence and incidence of heart failure rise with age. Diagnosis of heart failure in the older patient may be difficult because of atypical symptoms or the acceptance of symptoms as manifestations of old age. Heart failure is not a diagnosis but a syndrome. Echocardiograms should be obtained in most elderly patients to aid diagnosis and assessment. Loop diuretics, taking into account the altered homoeostasis of old age and presence of co‐morbidity, are the mainstay of symptomatic treatment. ACE inhibitors are likely to benefit survival, although formal trials have failed to include many older patients. Digoxin and direct vasodilators are less well tolerated in elderly patients.

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Section: Prevalencementioning

confidence: 99%