Drugs contraindicated in cat

Abstract

While medicating cats, veterinarians have to very cautious else they can face serious adverse effects. Cats are different from other animals with respect to metabolism. Various drugs like antibiotics, Non-steroidal anti-inflammatory drugs (NSAIDs), anti-parasitic etc. are causing adverse effects in cats. The prescribed drugs may cause acute poisoning even at therapeutic doses. This review aims at providing information to clinical veterinarian, pet owner to be cautious while administering of drugs in cats. The adverse effects of contraindicated drugs are summarised here for accurate use of drugs and to avoid acute poisoning leading to death.

Intraoperative Isoflurane End-Tidal Concentration during Infusion of Fentanyl, Tramadol, or Fentanyl–Tramadol Combination in Cats

“…Multimodal anesthesia combines different drugs to reduce their doses and toxic effects [ 1 ]. This technique can be very useful in feline patients, where the choice of analgesics and their dosage must consider the lack of many drug conjugation and metabolism pathways in this species, resulting in prolonged plasma concentrations, deficiencies in hepatic metabolism (decreased UGTC), and decreased excretion, with increased toxicities and other side effects [ 2 , 3 , 4 ]. While the reduction of inhaled anesthetic requirements by opioid administration has been demonstrated in dogs, conflicting data have been reported in cats [ 1 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 ].…”