Abstract:Substance Use Disorders (SUDs) are an impactful problem characterized by chronic relapse and engagement in drug‐related behaviors at the expense of non‐drug behaviors. Brain regions implicated in drug and non‐drug‐related behaviors often overlap, complicating investigations of neurobiological mechanisms underlying SUDs. Here we presented a within‐subject model for studying self‐administration, reinforcer competition, extinction, and cued reinstatement of cocaine‐ and food‐seeking in rats. Due to differences in… Show more
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